Vms1/Ankzf1 peptidyl-tRNA hydrolase releases nascent chains from stalled ribosomes
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DOI: 10.1038/s41586-018-0022-5
Abstract: Ribosomal surveillance pathways scan for ribosomes that are transiently paused or terminally stalled owing to structural elements in mRNAs or nascent chain sequences1, 2. Some stalls in budding yeast are sensed by the GTPase Hbs1,… read more here.
Keywords: nascent chains; trna hydrolase; stalled ribosomes; peptidyl trna ... See more keywords
Structure of Escherichia coli heat shock protein Hsp15 in complex with the ribosomal 50S subunit bearing peptidyl-tRNA
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DOI: 10.1093/nar/gkac1035
Abstract: Abstract In Escherichia coli, the heat shock protein 15 (Hsp15) is part of the cellular response to elevated temperature. Hsp15 interacts with peptidyl-tRNA-50S complexes that arise upon dissociation of translating 70S ribosomes, and is proposed… read more here.
Keywords: hsp15; trna; peptidyl trna; heat shock ... See more keywords