Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases
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DOI: 10.3390/ijms21020566
Abstract: Deimination, also known as citrullination, corresponds to the conversion of the amino acid arginine, within a peptide sequence, into the non-standard amino acid citrulline. This post-translational modification is catalyzed by a family of calcium-dependent enzymes… read more here.
Keywords: peptidylarginine deiminases; deiminases skin; skin physiology; physiology ... See more keywords
Putative Roles for Peptidylarginine Deiminases in COVID-19
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DOI: 10.3390/ijms21134662
Abstract: Peptidylarginine deiminases (PADs) are a family of calcium-regulated enzymes that are phylogenetically conserved and cause post-translational deimination/citrullination, contributing to protein moonlighting in health and disease. PADs are implicated in a range of inflammatory and autoimmune… read more here.
Keywords: peptidylarginine deiminases; putative roles; mrna levels; tissue ... See more keywords
Differential, Stage Dependent Detection of Peptidylarginine Deiminases and Protein Deimination in Lewy Body Diseases—Findings from a Pilot Study
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DOI: 10.3390/ijms232113117
Abstract: Over 10 million people worldwide live with Parkinson’s disease (PD) and 4% of affected people are diagnosed before the age of 50. Research on early PD-related pathways is therefore of considerable importance. Peptidylarginine deiminases (PADs)… read more here.
Keywords: peptidylarginine deiminases; deimination; protein deimination; lewy body ... See more keywords