Peptidylglycine monooxygenase activity of monomeric species of growth hormone
Sign Up to like & getrecommendations! Published in 2019 at "Heliyon"
DOI: 10.1016/j.heliyon.2019.e02436
Abstract: C-terminal α-amidation of peptides is an important event in the course of pro-hormone and neuropeptide processing; it is a modification that contributes to the biological activity and stability of about 25 peptides in neural and… read more here.
Keywords: monooxygenase activity; monooxygenase; growth hormone; activity ... See more keywords
Pre-Steady-State Reactivity of Peptidylglycine Monooxygenase Implicates Ascorbate in Substrate Triggering of the Active Conformer
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DOI: 10.1021/acs.biochem.2c00080
Abstract: Peptidylglycine monooxygenase (PHM) is essential for the posttranslational amidation of neuroendocrine peptides. An important aspect of the PHM mechanism is the complete coupling of oxygen reduction to substrate hydroxylation, which implies no oxygen reactivity of… read more here.
Keywords: peptidylglycine monooxygenase; reactivity; substrate; steady state ... See more keywords