Per1 mutation enhances masking responses in mice
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DOI: 10.1080/07420528.2022.2126321
Abstract: ABSTRACT Light can restrict the activity of an animal to a diurnal or nocturnal niche by synchronizing its endogenous clock (entrainment) which controls the sleep wake cycle. Light can also directly change an animal’s activity… read more here.
Keywords: masking responses; responses mice; per1 mutation; per1 per2 ... See more keywords
Per1/Per2 Disruption Reduces Testosterone Synthesis and Impairs Fertility in Elderly Male Mice
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DOI: 10.3390/ijms23137399
Abstract: Circadian rhythm disorders caused by genetic or environmental factors lead to decreased male fertility but the mechanisms are poorly understood. The current study reports that the mechanism of Per1/Per2 Double knockout (DKO) reduced the reproductive… read more here.
Keywords: fertility; per1 per2; testosterone synthesis; mice ... See more keywords
Per1/Per2 knockout Affects Spleen Immune Function in Elderly Mice via Inducing Spleen Lymphocyte Ferroptosis
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DOI: 10.3390/ijms232112962
Abstract: Disturbances in circadian rhythms are known to affect immune functions. However, the long-term impact of abnormal circadian rhythms on the immune-related functions of the spleen are poorly understood. Hence, we aimed to investigate the immune-related… read more here.
Keywords: spleen lymphocyte; knockout; per1 per2; mice ... See more keywords