Pharmacokinetics and brain uptake study of novel AMPA receptor antagonist perampanel in SD rats using a validated UHPLC‐QTOF‐MS method
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DOI: 10.1016/j.jpba.2017.11.008
Abstract: Graphical abstract Figure. No caption available. HighlightsThe method shows high sensitivity, very good precision and accuracy with short run time.Simple protein precipitation as sample preparation approach with good recovery from plasma/brain homogenate.The method found to… read more here.
Keywords: method; brain; perampanel rats; uptake study ... See more keywords