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Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.23484
Abstract: This sequential, cross-sectional study examines the prevalence of perforated appendicitis in children in the United States in relation to access to health care from 2001 to 2015. read more here.
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Published in 2019 at "Surgical Endoscopy"
DOI: 10.1007/s00464-019-06847-2
Abstract: Background The advantages of laparoscopic appendectomy did not meet the same acceptance in the setting of perforated appendicitis as in uncomplicated appendicitis in the general surgical community. The aim of this study was to compare… read more here.
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Published in 2017 at "American Journal of Emergency Medicine"
DOI: 10.1016/j.ajem.2016.10.010
Abstract: Background: The early prediction of gangrenous/perforated appendicitis is of great importance for the surgical planning, further treatments, and predicting the course of disease. Ischemia‐modified albumin (IMA) was previously reported as a biomarker of various ischemia‐based… read more here.
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Published in 2018 at "American journal of surgery"
DOI: 10.1016/j.amjsurg.2017.06.003
Abstract: BACKGROUND We sought to decrease organ space infection (OSI) following appendectomy for perforated acute appendicitis (PAA) by minimizing variation in clinical management. OBJECTIVE A postoperative treatment pathway was developed and four recommendations were implemented: 1)… read more here.
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Published in 2018 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2018.02.030
Abstract: BACKGROUND Total parenteral nutrition (TPN) is often used in children with perforated appendicitis, despite the absence of clear indications. We assessed the validity of specific clinical indications for initiation of TPN in this patient cohort.… read more here.
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Published in 2020 at "Journal of pediatric surgery"
DOI: 10.1016/j.jpedsurg.2020.06.031
Abstract: BACKGROUND/PURPOSE Prophylactic, intraabdominal drains have been used to prevent intraabdominal abscess (IAA) after perforated appendicitis. We hypothesized that routine drain placement would reduce the IAA rate in pediatric perforated appendicitis. METHODS A 27-month quality improvement… read more here.
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Published in 2018 at "Journal of Investigative Surgery"
DOI: 10.1080/08941939.2016.1257667
Abstract: ABSTRACT Aim: Acute appendicitis is the most common cause of abdominal surgical emergencies. Early diagnosis of appendicitis can reduce perforation and mortality rate. High-mobility group box 1 (HMGB1) protein has been identified as a pro-inflammatory… read more here.
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Published in 2017 at "Medicine"
DOI: 10.1097/md.0000000000008747
Abstract: Rationale: Colonoscopy is a relatively safe and common procedure with low risks of complications, and acute appendicitis with perforation is an extremely rare complication of colonoscopy. The current study presents an unusual case of acute… read more here.
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Published in 2017 at "Annals of Surgery"
DOI: 10.1097/sla.0000000000001946
Abstract: Objective: To determine the incremental cost-effectiveness of a clinical practice guideline (CPG) compared with “usual care” for treatment of perforated appendicitis in children. Secondary objective was to compare cost analyses using hospital accounting system data… read more here.
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Published in 2022 at "ANZ journal of surgery"
DOI: 10.1111/ans.17655
Abstract: BACKGROUNDS The COVID-19 pandemic presents ongoing challenges for healthcare. Stay at Home orders ('lockdowns') and community fears have been suggested to create reluctance to seek healthcare. We aimed to determine whether the rates of perforated… read more here.
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Published in 2019 at "Journal of Paediatrics and Child Health"
DOI: 10.1111/jpc.14591
Abstract: Perforated appendicitis has poorer clinical outcomes compared to non‐perforated appendicitis. However, accurate outcome comparisons in research and clinical audits are challenged by its wide spectrum of manifestation. Previous attempts at the classification of severity have… read more here.