Articles with "perfused guinea" as a keyword



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Determinants of slowed conduction in premature ventricular beats induced during programmed stimulations in perfused guinea‐pig heart

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Published in 2018 at "Experimental Physiology"

DOI: 10.1113/ep087019

Abstract: What is the central question of this study? Is the slowed conduction upon premature ventricular activations during clinical electrophysiological testing attributable to the prolonged activation latency, or increased impulse propagation time, or both? What is… read more here.

Keywords: guinea pig; pig heart; premature ventricular; perfused guinea ... See more keywords
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Effects of Na+ channel blockers on the restitution of refractory period, conduction time, and excitation wavelength in perfused guinea-pig heart

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Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0172683

Abstract: Na+ channel blockers flecainide and quinidine can increase propensity to ventricular tachyarrhythmia, whereas lidocaine and mexiletine are recognized as safe antiarrhythmics. Clinically, ventricular fibrillation is often precipitated by transient tachycardia that reduces action potential duration,… read more here.

Keywords: guinea pig; perfused guinea; excitation wavelength; channel blockers ... See more keywords