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Published in 2018 at "Experimental Physiology"
DOI: 10.1113/ep087019
Abstract: What is the central question of this study? Is the slowed conduction upon premature ventricular activations during clinical electrophysiological testing attributable to the prolonged activation latency, or increased impulse propagation time, or both? What is…
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Keywords:
guinea pig;
pig heart;
premature ventricular;
perfused guinea ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0172683
Abstract: Na+ channel blockers flecainide and quinidine can increase propensity to ventricular tachyarrhythmia, whereas lidocaine and mexiletine are recognized as safe antiarrhythmics. Clinically, ventricular fibrillation is often precipitated by transient tachycardia that reduces action potential duration,…
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Keywords:
guinea pig;
perfused guinea;
excitation wavelength;
channel blockers ... See more keywords