Flow–perfusion bioreactor system for engineered breast cancer surrogates to be used in preclinical testing
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2026
Abstract: There is a need for preclinical testing systems that predict the efficacy, safety and pharmacokinetics of cancer therapies better than existing in vitro and in vivo animal models. An approach to the development of predictive… read more here.
Keywords: perfusion bioreactor; volume; perfusion; bioreactor system ... See more keywords
A combined computational-fluid-dynamics model and control strategies for perfusion bioreactor systems in tissue engineering
Sign Up to like & getrecommendations! Published in 2021 at "IFAC-PapersOnLine"
DOI: 10.1016/j.ifacol.2021.08.262
Abstract: Abstract This work sets the foundations for the design of control algorithms to facilitate manufacturing of a cell growth process using a continuous perfusion bioreactor. The algorithms are designed to work with different types of… read more here.
Keywords: perfusion bioreactor; fluid dynamics; control; computational fluid ... See more keywords
Optimization and Validation of a Custom-Designed Perfusion Bioreactor for Bone Tissue Engineering: Flow Assessment and Optimal Culture Environmental Conditions
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.811942
Abstract: Various perfusion bioreactor systems have been designed to improve cell culture with three-dimensional porous scaffolds, and there is some evidence that fluid force improves the osteogenic commitment of the progenitors. However, because of the unique… read more here.
Keywords: perfusion bioreactor; perfusion; optimization validation; geometry ... See more keywords