Two new compounds from Pergularia tomentosa growing wildly in Jordan.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Asian natural products research"
DOI: 10.1080/10286020.2022.2131548
Abstract: Phytochemical investigation of the aerial parts and latex of Pergularia tomentosa from Jordan, utilizing column chromatography accompanied with NMR (1 & 2D), IR, UV, and HR-ESI-Mass spectroscopy have led to the isolation and characterization of… read more here.
Keywords: tomentosa growing; compounds pergularia; pergularia tomentosa; two new ... See more keywords
Laticifer Identification, Rubber Characterization, Phenolic Content, and Antioxidant Activity of Pergularia tomentosa Latex Extract
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/7158905
Abstract: Pergularia tomentosa is a perennial twining herb widely spread out arid and semiarid Tunisian regions. It is searched for its richness in enzymes, secondary metabolites, antifungal activity, and milk-clotting activity. Traditional use implies the fresh… read more here.
Keywords: activity; latex extract; pergularia tomentosa; phenolic content ... See more keywords
LC-MS-based metabolite profiling of aqueous extract of Pergularia tomentosa L. and its anti-hyperglycemic effect
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2022.65646.14441
Abstract: Objective(s): In this study, to find scientific evidence for the traditional use of Pergularia tomentosa as an anti-diabetic remedy, the effects of its aqueous extract on streptozotocin-induced diabetes mellitus in rats were evaluated. Materials and… read more here.
Keywords: aqueous extract; pergularia tomentosa; effect; tomentosa ... See more keywords
Pro-Apoptotic and Pro-Autophagic Properties of Cardenolides from Aerial Parts of Pergularia tomentosa
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DOI: 10.3390/molecules27154874
Abstract: Pergularia tomentosa L., a milkweed tropical plant belonging to the family Asclepiadaceae, is a rich source of unusual cardiac glycosides, characterised by transfused A/B rings and a sugar moiety linked by a double link, generating… read more here.
Keywords: cell; pergularia tomentosa; pro apoptotic; cardenolides aerial ... See more keywords
In Silico Pharmacokinetic Profiling of the Identified Bioactive Metabolites of Pergularia tomentosa L. Latex Extract and In Vitro Cytotoxic Activity via the Induction of Caspase-Dependent Apoptosis with S-Phase Arrest
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15091132
Abstract: The in vitro cytotoxic efficacy of plant latex from Pergularia tomentosa L. was studied using five human cancer cell lines: HeLa cells (cervical carcinoma cells), A-549 (lung carcinoma), Panc-1 (pancreatic carcinoma cells), MDA-MB-231 (metastatic mammary… read more here.
Keywords: cell; pergularia tomentosa; latex; plant latex ... See more keywords