Accelerated multicontrast volumetric imaging with isotropic resolution for improved peri‐infarct characterization using parallel imaging, low‐rank and spatially varying edge‐preserving sparse modeling
Sign Up to like & getrecommendations! Published in 2018 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.26970
Abstract: To achieve consistent effectiveness in reconstruction of fine image features for cases of varying contrast‐to‐noise ratio (CNR) to facilitate translating accelerated multicontrast volumetric imaging with isotropic resolution toward clinical utility in peri‐infarct characterization. read more here.
Keywords: volumetric imaging; imaging isotropic; accelerated multicontrast; peri infarct ... See more keywords
Intravital Imaging Reveals the Ameliorating Effect of Colchicine in a Photothrombotic Stroke Model via Inhibition of Neutrophil Recruitment.
Sign Up to like & getrecommendations! Published in 2022 at "Translational stroke research"
DOI: 10.1007/s12975-022-01022-7
Abstract: Although post-stroke neutrophil recruitment is known to be deleterious to neural tissues in the peri-infarct area, the precise behavior of recruited neutrophils remains elusive. In this study, potential therapeutic agents for modifying neutrophil behavior in… read more here.
Keywords: stroke; colchicine; model; neutrophil recruitment ... See more keywords
Up-regulation of sphingosine-1-phosphate receptors and sphingosine kinase 1 in the peri-ischemic area after transient middle cerebral artery occlusion in mice
Sign Up to like & getrecommendations! Published in 2020 at "Brain Research"
DOI: 10.1016/j.brainres.2020.146831
Abstract: There is thought to be a strong relationship between sphingosine-1-phosphate (S1P) signaling and pathophysiolosy of cerebral ischemia. We examined the change of expression and distribution of S1P receptors (S1PRs) and sphingosine kinases (SphKs) after cerebral… read more here.
Keywords: peri; peri infarct; infarct lesion; transient middle ... See more keywords
Molecular profile of the rat peri-infarct region four days after stroke: Study with MANF
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2020.113288
Abstract: The peri-infarct region after ischemic stroke is the anatomical location for many of the endogenous recovery processes, and the molecular events in the peri-infarct region remain poorly characterized. In this study, we examine the molecular… read more here.
Keywords: manf; infarct region; peri infarct; molecular profile ... See more keywords
Astrocyte-secreted chordin-like 1 regulates spine density after ischemic injury
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DOI: 10.1038/s41598-022-08031-4
Abstract: Ischemic injury occurs when the brain is deprived of blood flow, preventing cells from receiving essential nutrients. The injury core is the brain region directly deprived and is surrounded by the peri-infarct area, the region… read more here.
Keywords: infarct area; chordin like; injury; peri infarct ... See more keywords
Dihydromyricetin alleviates cerebral ischemia-reperfusion injury by attenuating apoptosis and astrogliosis in peri-infarct cortex.
Sign Up to like & getrecommendations! Published in 2021 at "Neurological research"
DOI: 10.1080/01616412.2021.1997010
Abstract: OBJECTIVES In ischemic stroke, reperfusion after thrombolysis is associated with secondary brain damage. Dihydromyricetin (DHM), a flavonoid, has shown neuroprotective effects through anti-oxidant, anti-inflammatory and anti-apoptotic properties. This study investigates the potential of DHM, given… read more here.
Keywords: peri infarct; infarct; dhm; infarct cortex ... See more keywords
A11221 Effects of intra-arterial transplantation of adipose-derived stem cells on the expression of netrin-1 and its receptor DCC in the peri-infarct cortex after experimental stroke
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548237.04075.9f
Abstract: Objectives: Since netrin-1 and its receptor deleted in colorectal cancer (DCC) are important regulators in neuronal and vascular activities, the present study attempted to explore whether netrin-1 and DCC are involved in the neuroprotection of… read more here.
Keywords: expression netrin; dcc; peri infarct; stem ... See more keywords
White Wine Consumption Influences Inflammatory Phase of Repair After Myocardial Infarction in Rats
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000000519
Abstract: Abstract: Effects of white wine (WW) consumption on the expression of inflammatory markers/mediators (MMP-2, MMP-9, NF-ĸB p65 and TGF-&bgr;1) in myocardial tissue after experimentally induced permanent myocardial ischemia was investigated. Male Sprague-Dawley rats were given… read more here.
Keywords: white wine; wine consumption; peri infarct; expression ... See more keywords
Loss of GFAP and Vimentin Does Not Affect Peri-Infarct Depolarizations after Focal Cerebral Ischemia
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DOI: 10.1159/000507990
Abstract: Peri-infarct depolarization (PID), one kind of spreading depolarization, contributes to infarct volume enlargement after ischemic stroke. Astrocytes participate in PIDs by various mechanisms. The roles of glial fibrillary acidic protein (GFAP) and vimentin (Vim), intermediate… read more here.
Keywords: gfap vimentin; peri infarct; gfap;
Imaging the Effects of &bgr;-Hydroxybutyrate on Peri-Infarct Neurovascular Function and Metabolism
Sign Up to like & getrecommendations! Published in 2018 at "Stroke"
DOI: 10.1161/strokeaha.118.020586
Abstract: Background and Purpose— Recent evidence suggests great potential of metabolically targeted interventions for treating neurological disorders. We investigated the use of the endogenous ketone body &bgr;-hydroxybutyrate (BHB) as an alternate metabolic substrate for the brain… read more here.
Keywords: metabolism; bgr hydroxybutyrate; imaging effects; functional recovery ... See more keywords
Peri-Infarct Hot-Zones Have Higher Susceptibility to Optogenetic Functional Activation-Induced Spreading Depolarizations
Sign Up to like & getrecommendations! Published in 2020 at "Stroke"
DOI: 10.1161/strokeaha.120.029618
Abstract: Supplemental Digital Content is available in the text. Background and Purpose: Spreading depolarizations (SDs) are recurrent and ostensibly spontaneous depolarization waves that may contribute to infarct progression after stroke. Somatosensory activation of the metastable peri-infarct… read more here.
Keywords: hot zones; activation; spreading depolarizations; functional activation ... See more keywords