MRI Volumetric Changes in Perianal Fistulizing Crohn's Disease: Moving Toward a Novel Outcome Measure for Therapeutic Response
Sign Up to like & getrecommendations! Published in 2025 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12765
Abstract: Crohn's disease is a chronic, immune‐mediated disorder of the gastrointestinal tract, that is characterized by a relapsing‐ remitting course with heterogeneous phenotypes. Perianal fis-tulizing Crohn'sdisease represents one ofthe most aggressive and debilitating forms of Crohn's… read more here.
Keywords: perianal fistulizing; disease; fistulizing crohn; crohn disease ... See more keywords
Less combination therapy and more fistulotomy in perianal fistulizing Crohn’s disease in the elderly
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DOI: 10.1007/s00384-025-04991-x
Abstract: This study aimed to describe Crohn’s disease perianal fistulizing lesions in patients undergoing surgery over 60 years to compare clinical presentation, management and outcomes with those observed in younger patients. Between January 2012 and December… read more here.
Keywords: perianal fistulizing; disease; anal fistula; crohn disease ... See more keywords
CLINICAL CHARACTERISTICS AND TREATMENT OF CROHN'S DISEASE FISTULIZANTE PERIANAL IN COLOMBIA: RESULTS OF A MULTICENTRIC REGISTRY.
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterologia y hepatologia"
DOI: 10.1016/j.gastrohep.2022.02.006
Abstract: INTRODUCTION Fistulizing perianal Crohn's disease (CD) is a phenotype with a poor prognosis. There are no studies in our country. Our objective is to determine the clinical, sociodemographic and treatment characteristics of perianal fistulizing CD… read more here.
Keywords: crohn disease; treatment; perianal fistulizing; disease ... See more keywords
Perianal Fistulizing Crohn's Disease: Outcomes of Surgical Repairs and Current State of Stem Cell-Based Therapies
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DOI: 10.1055/s-0044-1786543
Abstract: Abstract Perianal fistulizing Crohn's disease is one of the most disabling phenotypes of Crohn's disease, due to the severe impairment in quality of life including social and personal wellbeing. A multimodal approach with patient-tailored care… read more here.
Keywords: disease; crohn disease; treatment outcomes; disease outcomes ... See more keywords
P774 Less combination therapy and more fistulotomy in perianal fistulizing Crohn’s disease in the elderly
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjad212.0904
Abstract: Prevalence of Crohn's disease (CD) is on the rise in the elderly and perianal fistulizing lesions affect nearly one in five patients over 60. Despite the specificity of luminal disease, few studies have focused on… read more here.
Keywords: age; disease; anal fistula; perianal fistulizing ... See more keywords
ECCO Grant Ablating perianal fistulizing Crohn’s disease through genetically engineered patient specific induced pluripotent stem cells (iPSC)-derived stromal cells
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjad212.1434
Abstract: Despite the wide range of available therapies treatment of perianal fistulizing Crohn’s disease (pCD) remains challenging. Therefore, exploring new effective therapies is of crucial importance. Local injection of allogeneic mesenchymal stromal cells has been reported… read more here.
Keywords: patient specific; perianal fistulizing; stromal cells; fistulizing crohn ... See more keywords
Evaluating the effectiveness of infliximab on perianal fistulizing Crohn’s disease by magnetic resonance imaging
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DOI: 10.1093/gastro/goy036
Abstract: Abstract Background and aim Data on the radiologic evaluation of perianal fistulizing Crohn’s disease (PFCD) naïve to anti-tumor necrosis factor therapy are scarce, especially in Asian populations. We assessed the effectiveness of infliximab (IFX) on… read more here.
Keywords: magnetic resonance; effectiveness infliximab; disease; perianal fistulizing ... See more keywords
Combined strategies following surgical drainage for perianal fistulizing Crohn's disease: failure rates and prognostic factors
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DOI: 10.1111/codi.15241
Abstract: The medico‐surgical strategy for the treatment of perianal fistulizing Crohn's disease (CD) following surgical drainage remains challenging and debated. Our aims were to describe the failure rate of therapeutic interventions after drainage of the fistula… read more here.
Keywords: disease; perianal fistulizing; fistulizing crohn; failure ... See more keywords
Tumor necrosis factor receptor-associated factor 5 enhances perianal fistulizing Crohn’s disease through epithelial–mesenchymal transition
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DOI: 10.25259/cytojournal_148_2024
Abstract: Objective: Crohn’s disease (CD) is a chronic inflammatory condition of the bowel that remarkably impairs a patient’s quality of life and often has a poor prognosis. Perianal fistulizing CD (PFCD) is one of the most… read more here.
Keywords: pfcd; crohn disease; perianal fistulizing; factor ... See more keywords
Editorial: Abdominal and Perianal Fistulizing Crohn's Disease: Imaging, Surgical Techniques and Basic Research
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DOI: 10.3389/fsurg.2022.952874
Abstract: Crohn’s disease (CD) is an idiopathic inflammatory bowel disease characterized by chronic transmural inflammation typically affecting the distal ileum and the proximal colon. In penetrating CD (PCD), the formation of fistulas derives from the transmural… read more here.
Keywords: perianal fistulizing; disease; crohn disease; abdominal perianal ... See more keywords
Vedolizumab for perianal fistulizing Crohn’s disease: systematic review and meta-analysis
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DOI: 10.5217/ir.2021.00091
Abstract: Background/Aims Perianal fistulas are a debilitating manifestation of Crohn’s disease (CD). Despite the advent of anti-tumor necrosis factor (anti-TNF) therapy, the medical management of fistulizing CD continues to be challenged by unmet needs. We conducted… read more here.
Keywords: perianal fistulizing; perianal fistulas; meta analysis; crohn disease ... See more keywords