Molecular architecture of a cylindrical self-assembly at human centrosomes
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-08838-2
Abstract: The cell is constructed by higher-order structures and organelles through complex interactions among distinct structural constituents. The centrosome is a membraneless organelle composed of two microtubule-derived structures called centrioles and an amorphous mass of pericentriolar… read more here.
Keywords: self assembly; pericentriolar material; higher order; material ... See more keywords
Proteomic mapping and targeting of mitotic pericentriolar material in tumors bearing centrosome amplification.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer research"
DOI: 10.1158/0008-5472.can-22-0225
Abstract: Recent work has made it clear that pericentriolar material (PCM), the matrix of proteins surrounding centrioles, contributes to most functions of centrosomes. Given the occurrence of centrosome amplification in most solid tumors and the unconventional… read more here.
Keywords: pericentriolar material; centrosome amplification; pcm; proteomic mapping ... See more keywords