Propranolol increases vascular permeability through pericyte apoptosis and exacerbates oxygen-induced retinopathy.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.08.041
Abstract: Retinopathy of prematurity (ROP) is an eye disease that causes blindness due to delayed vascular growth, retinal ischemia, and resulting abnormal angiogenesis. Nonselective β-antagonist propranolol is in clinical trials for the treatment of ROP due… read more here.
Keywords: rop; permeability; propranolol; pericyte apoptosis ... See more keywords
Interleukin-1β induces pericyte apoptosis via the NF-κB pathway in diabetic retinopathy.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.01.108
Abstract: Pericytes play a crucial role in preventing endothelial permeability by maintaining the integrity of tight junctions in endothelial cells; however, early pathological change in diabetic retinopathyis pericyte loss, which can lead to visual impairment by… read more here.
Keywords: diabetic retinopathy; permeability; endothelial cells; pericyte apoptosis ... See more keywords
Ulmus davidiana 60% edible ethanolic extract for prevention of pericyte apoptosis in diabetic retinopathy
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1138676
Abstract: Diabetic retinopathy (DR) is a disease that causes visual deficiency owing to vascular leakage or abnormal angiogenesis. Pericyte apoptosis is considered one of the main causes of vascular leakage in diabetic retina, but there are… read more here.
Keywords: apoptosis; davidiana; pericyte apoptosis; vascular leakage ... See more keywords