Phase II trial of an AKT inhibitor (perifosine) for recurrent glioblastoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-019-03243-7
Abstract: Perifosine (PRF) is an oral alkylphospholipid with antineoplastic effects and reasonable tolerability. It inhibits signaling through the PI3/AKT axis and other cascades of biologic importance in glioblastoma, and has promising pre-clinical activity in vitro and… read more here.
Keywords: akt; phase; trial; glioblastoma ... See more keywords
[Perifosine inhibits biofilm formation of Pseudomonas aeruginosa by interacting with PqsE protein].
Sign Up to like & getrecommendations! Published in 2022 at "Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]"
DOI: 10.3760/cma.j.cn112150-20211020-00970
Abstract: To explore the biofilm inhibitory efficacy of perifosine against Pseudomonas aeruginosa (P. aeruginos) and its mechanisms. Twenty-fourwell plate was used to form biofilms at the bottom and crystal violet staining was used to determine the… read more here.
Keywords: without perifosine; effects perifosine; wells without; perifosine ... See more keywords