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Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000020951
Abstract: Abstract Perihematomal edema (PHE) surrounding intracerebral hemorrhage (ICH) may contribute to disease-associated morbidity. Before quantifying PHE's effects on morbidity, a fast, accurate, and reproducible method for measuring PHE volume is needed. The aim of this… read more here.
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Published in 2023 at "European Journal of Neurology"
DOI: 10.1111/ene.15760
Abstract: Neoplastic intracerebral hemorrhage (ICH) may be incorrectly identified as non‐neoplastic ICH on imaging. Relative perihematomal edema (relPHE) on computed tomography (CT) has been proposed as a marker to discriminate neoplastic from non‐neoplastic ICH but has… read more here.
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Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/3948921
Abstract: Acute intracerebral hemorrhage (ICH) is a devastating type of stroke worldwide. Neuronal destruction involved in the brain damage process caused by ICH includes a primary injury formed by the mass effect of the hematoma and… read more here.
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Published in 2021 at "Stroke"
DOI: 10.1161/str.52.suppl_1.p416
Abstract: Introduction: The prognosis of intracerebral hemorrhage (ICH) is poor because of the mass effect arising from the hematoma and the associated perihematomal edema (PHE). Remote ischemic conditioning... read more here.
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Published in 2022 at "Clinical Trials"
DOI: 10.1177/17407745221105886
Abstract: Background: Hematoma and perihematomal edema volumes are important radiographic markers in spontaneous intracerebral hemorrhage. Accurate, reliable, and efficient quantification of these volumes will be paramount to their utility as measures of treatment effect in future… read more here.
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Published in 2021 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2021.700166
Abstract: Background and Purpose: Perihematomal edema (PHE) is associated with poor functional outcomes after intracerebral hemorrhage (ICH). Early identification of risk factors associated with PHE growth may allow for targeted therapeutic interventions. Methods: We used data… read more here.
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Published in 2023 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2023.1114602
Abstract: Background Perihematomal edema (PHE) after spontaneous intracerebral hemorrhage (sICH) is associated with clinical deterioration, but the etiology of PHE development is only partly understood. Aims We aimed to investigate the association between systemic blood pressure… read more here.
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Published in 2025 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2025.1575446
Abstract: Background Perihematomal edema (PHE) after a brain hemorrhage is an increase in the water content of the brain tissue surrounding the haematoma, which can be observed and measured on imaging. PHE is one of the… read more here.
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Published in 2024 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2024.1394795
Abstract: Background The relationship between early perihematomal edema (PHE) and hematoma expansion (HE) is unclear. We investigated this relationship in patients with acute spontaneous intracerebral hemorrhage (ICH), using radiomics. Methods In this multicenter retrospective study, we… read more here.