The significance of lipid accumulation in breast carcinoma cells through perilipin 2 and its clinicopathological significance
Sign Up to like & getrecommendations! Published in 2019 at "Pathology International"
DOI: 10.1111/pin.12831
Abstract: Both systemic and intratumoral lipid metabolism have been recently reported to play pivotal roles in both tumor development and progression in various human malignancies including breast cancer. However, its details have remained largely unknown in… read more here.
Keywords: status; breast; breast carcinoma; perilipin ... See more keywords
Perilipin-2 deletion promotes carbohydrate-mediated browning of white adipose tissue at ambient temperature[S]
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Lipid Research"
DOI: 10.1194/jlr.m086249
Abstract: Mice lacking perilipin-2 (Plin2-null) are resistant to obesity, insulin resistance, and fatty liver induced by Western or high-fat diets. In the current study, we found that, compared with WT mice on Western diet, Plin2-null adipose… read more here.
Keywords: plin2 null; perilipin; adipose tissue; white adipose ... See more keywords
Lipid Droplet Formation Is Regulated by Ser/Thr Phosphatase PPM1D via Dephosphorylation of Perilipin 1
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231912046
Abstract: Hypertrophy and hyperplasia of white adipocytes induce obesity, leading to diseases such as type 2 diabetes and hypertension, and even cancer. Hypertrophy of white adipocytes is attributed to the excessive storage of the energy form… read more here.
Keywords: white adipocytes; perilipin; ppm1d; formation ... See more keywords
Primary Focal Segmental Glomerulosclerosis Plasmas Increase Lipid Droplet Formation and Perilipin-2 Expression in Human Podocytes
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DOI: 10.3390/ijms24010194
Abstract: Many patients with primary focal segmental glomerulosclerosis (FSGS) develop recurrence of proteinuria after kidney transplantation. Several circulating permeability factors (CPFs) responsible for recurrence have been suggested, but were never validated. We aimed to find proteins… read more here.
Keywords: primary focal; expression; perilipin; plasmas ... See more keywords
The C-Terminus of Perilipin 3 Shows Distinct Lipid Binding at Phospholipid-Oil-Aqueous Interfaces
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DOI: 10.3390/membranes11040265
Abstract: Lipid droplets (LDs) are ubiquitously expressed organelles; the only intracellular organelles that contain a lipid monolayer rather than a bilayer. Proteins localize and bind to this monolayer as they do to intracellular lipid bilayers. The… read more here.
Keywords: full length; perilipin; oil aqueous; binding ... See more keywords