MicroRNA profile of human endo-/perilymph
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DOI: 10.1007/s00415-018-8862-3
Abstract: The fluids of the human inner ear (endolymph and perilymph) are a self-contained system without any direct connection to other body fluids. Therefore, the composition of these fluids is unique. Both fluids differ in their… read more here.
Keywords: mirna; endo perilymph; human endo; perilymph ... See more keywords
Development and performance of a biomimetic artificial perilymph for in vitro testing of medical devices.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of neural engineering"
DOI: 10.1088/1741-2552/aaf482
Abstract: OBJECTIVE Cochlear implants interface with the fluid in the cochlea called perilymph. The volume of this fluid present in human and animal model cochlea is prohibitively low for isolation for in vitro studies. Thus, there… read more here.
Keywords: performance biomimetic; development performance; biomimetic artificial; perilymph ... See more keywords
Proteome profile of patients with excellent and poor speech intelligibility after cochlear implantation: Can perilymph proteins predict performance?
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DOI: 10.1371/journal.pone.0263765
Abstract: Modern proteomic analysis and reliable surgical access to gain liquid inner ear biopsies have enabled in depth molecular characterization of the cochlea microenvironment. In order to clarify whether the protein composition of the perilymph can… read more here.
Keywords: patients excellent; analysis; excellent poor; implantation ... See more keywords
Defining the Inflammatory Microenvironment in the Human Cochlea by Perilymph Analysis: Toward Liquid Biopsy of the Cochlea
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DOI: 10.3389/fneur.2019.00665
Abstract: The molecular pathomechanisms in the majority of patients suffering from acute or progressive sensorineural hearing loss cannot be determined yet. The size and the complex architecture of the cochlea make biopsy and in-depth histological analyses… read more here.
Keywords: analysis; cochlea; inflammatory; liquid biopsy ... See more keywords
Detection of BDNF-Related Proteins in Human Perilymph in Patients With Hearing Loss
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DOI: 10.3389/fnins.2019.00214
Abstract: The outcome of cochlear implantation depends on multiple variables including the underlying health of the cochlea. Brain derived neurotrophic factor (BDNF) has been shown to support spiral ganglion neurons and to improve implant function in… read more here.
Keywords: proteins human; analysis; regulated proteins; bdnf regulated ... See more keywords