Deep hypothermia prevents striatal alterations produced by perinatal asphyxia: Implications for the prevention of dyskinesia and psychosis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24925
Abstract: GABAergic medium spiny neurons are the main neuronal population in the striatum. Calbindin is preferentially expressed in medium spiny neurons involved in the indirect pathway. The aim of the present work is to analyze the… read more here.
Keywords: prevents striatal; hypothermia; striatal alterations; perinatal asphyxia ... See more keywords
Oligodendrocyte Response to Pathophysiological Conditions Triggered by Episode of Perinatal Hypoxia-Ischemia: Role of IGF-1 Secretion by Glial Cells
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Neurobiology"
DOI: 10.1007/s12035-020-02015-z
Abstract: Differentiation of oligodendrocyte progenitors towards myelinating cells is influenced by a plethora of exogenous instructive signals. Insulin-like growth factor 1 (IGF-1) is one of the major factors regulating cell survival, proliferation, and maturation. Recently, there… read more here.
Keywords: glial cells; perinatal asphyxia; igf secretion; igf ... See more keywords
Targeting Sentinel Proteins and Extrasynaptic Glutamate Receptors: a Therapeutic Strategy for Preventing the Effects Elicited by Perinatal Asphyxia?
Sign Up to like & getrecommendations! Published in 2017 at "Neurotoxicity Research"
DOI: 10.1007/s12640-017-9795-9
Abstract: Perinatal asphyxia (PA) is a relevant cause of death at the time of labour, and when survival is stabilised, associated with short- and long-term developmental disabilities, requiring inordinate care by health systems and families. Its… read more here.
Keywords: term; long term; perinatal asphyxia; insult ... See more keywords
Neurodevelopmental outcome of term infants with perinatal asphyxia with hypoxic ischemic encephalopathy stage II
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DOI: 10.1016/j.braindev.2016.09.005
Abstract: BACKGROUND Perinatal asphyxia with hypoxic ischemic encephalopathy (HIE) causes significant mortality and morbidity in developing countries. There is limited information about long term neurodevelopmental outcome of infants with neonatal encephalopathy. METHODS Term infants with the… read more here.
Keywords: term; age; hypoxic ischemic; perinatal asphyxia ... See more keywords
Original articleEarly neonatal deaths associated with perinatal asphyxia in infants ≥2500 g in BrazilÓbitos neonatais precoces associados à asfixia perinatal em neonatos ≥2.500 g no Brasil☆☆☆
Sign Up to like & getrecommendations! Published in 2017 at "Jornal De Pediatria"
DOI: 10.1016/j.jped.2016.11.008
Abstract: Objective To assess the annual burden of early neonatal deaths associated with perinatal asphyxia in infants weighing ≥2500 g in Brazil from 2005 to 2010. read more here.
Keywords: 2500 brazil; associated perinatal; perinatal asphyxia; asphyxia infants ... See more keywords
Individual longitudinal neurodevelopmental trajectories of children treated with hypothermia for perinatal asphyxia from 3 months to 5 years of age.
Sign Up to like & getrecommendations! Published in 2020 at "Research in developmental disabilities"
DOI: 10.1016/j.ridd.2020.103659
Abstract: BACKGROUND Hypothermia for perinatal asphyxia is a common treatment to decrease morbidity. This study aims to describe a) individual longitudinal neurodevelopmental trajectories over 5 years in children with perinatal asphyxia treated with hypothermia and b)… read more here.
Keywords: longitudinal neurodevelopmental; age; individual longitudinal; perinatal asphyxia ... See more keywords
Quantitative EEG features during the first day correlate to clinical outcome in perinatal asphyxia
Sign Up to like & getrecommendations! Published in 2024 at "Pediatric Research"
DOI: 10.1038/s41390-024-03235-y
Abstract: To assess whether computational electroencephalogram (EEG) measures during the first day of life correlate to clinical outcomes in infants with perinatal asphyxia with or without hypoxic-ischemic encephalopathy (HIE). We analyzed four-channel EEG monitoring data from… read more here.
Keywords: correlate clinical; clinical outcomes; perinatal asphyxia; first day ... See more keywords
Assessment of phospholipid synthesis related biomarkers for perinatal asphyxia: a piglet study
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DOI: 10.1038/srep40315
Abstract: The prompt and reliable identification of infants at risk of hypoxic-ischemic encephalopathy secondary to perinatal asphyxia in the first critical hours is important for clinical decision-making and yet still remains a challenge. This work strives… read more here.
Keywords: phospholipid synthesis; study; perinatal asphyxia; assessment phospholipid ... See more keywords
Renal Regional Oxygen Saturation and Acute Kidney Injury in Neonates with Perinatal Asphyxia
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DOI: 10.1055/a-2369-6811
Abstract: Abstract Objective Neonates with moderate-to-severe perinatal asphyxia often develop acute kidney injury (AKI). Additionally, therapeutic hypothermia (TH) can affect renal blood flow. This study aimed to evaluate the association between renal regional oxygen saturation (rSrO… read more here.
Keywords: rsro levels; rsro; perinatal asphyxia; acute kidney ... See more keywords
Associations between low birth weight and perinatal asphyxia: A hospital-based study
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DOI: 10.1097/md.0000000000033137
Abstract: To investigate the associations between low birth weight (LBW) and perinatal asphyxia by a hospital-based study. The participants of this study were mothers who gave birth at our hospital in 2018. They were divided into… read more here.
Keywords: associations low; perinatal asphyxia; hospital; asphyxia ... See more keywords
Population pharmacokinetics of vancomycin in term neonates with perinatal asphyxia treated with therapeutic hypothermia
Sign Up to like & getrecommendations! Published in 2024 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.16026
Abstract: Little is known about the population pharmacokinetics (PPK) of vancomycin in neonates with perinatal asphyxia treated with therapeutic hypothermia (TH). We aimed to describe the PPK of vancomycin and propose an initial dosing regimen for… read more here.
Keywords: therapeutic hypothermia; treated therapeutic; perinatal asphyxia; asphyxia treated ... See more keywords