Therapeutic potential of stem cells for preterm infant brain damage: can we move from the heterogeneity of preclinical and clinical studies to established therapeutics?
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2021.114461
Abstract: Acquired perinatal brain injuries are a set of conditions that remains a key challenge for neonatologists and that have significant social, emotional and financial implications for our communities. In our perspective article, will introduce perinatal… read more here.
Keywords: stem cells; perinatal brain; brain; brain damage ... See more keywords
Factors Influencing the Efficacy of Umbilical Cord Blood-Derived Cell Therapy for Perinatal Brain Injury
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DOI: 10.1093/stcltm/szad006
Abstract: Abstract Introduction We have previously described preclinical literature which supports umbilical cord blood-derived cell (UCBC) therapy as an efficacious treatment for perinatal brain injury. However, efficacy of UCBCs may be influenced by different patient population… read more here.
Keywords: cell; brain; therapy; perinatal brain ... See more keywords
Study Protocol: Multimodal Longitudinal Assessment of Infant Brain Organization and Recovery in Perinatal Brain Injury
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Physical Therapy"
DOI: 10.1097/pep.0000000000000886
Abstract: Purpose: Perinatal brain injury is a primary cause of cerebral palsy, a condition resulting in lifelong motor impairment. Infancy is an important period of motor system development, including development of the corticospinal tract (CST), the… read more here.
Keywords: brain; motor; perinatal brain; brain injury ... See more keywords
The So-Called “Protective Effect” of Preeclampsia on Perinatal Brain Damage
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DOI: 10.1159/000490455
Abstract: This edition of Neonatology reports the results of a study of children born prior to 30 weeks of gestational age (GA) who were admitted to a neonatal intensive care unit of a Swedish tertiary hospital… read more here.
Keywords: protective effect; perinatal brain; preeclampsia; called protective ... See more keywords
Perinatal brain damage – what the obstetrician needs to know
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Perinatal Medicine"
DOI: 10.1515/jpm-2022-0523
Abstract: Abstract Perinatal brain damage is still one of the leading contributors to perinatal death and postnatal disability worldwide. However, the term perinatal brain damage encompasses very different aetiological entities that result in an insult to… read more here.
Keywords: brain damage; obstetrician needs; brain; perinatal brain ... See more keywords
Cholesterol in Brain Development and Perinatal Brain Injury: more than a Building Block.
Sign Up to like & getrecommendations! Published in 2021 at "Current neuropharmacology"
DOI: 10.2174/1570159x19666211111122311
Abstract: The central nervous system (CNS) is enriched with important classes of lipids, in which cholesterol is known to make up a major portion of myelin sheaths, besides being a structural and functional unit of CNS… read more here.
Keywords: cholesterol; perinatal brain; brain injury; brain development ... See more keywords
Connexins, Pannexins and Gap Junctions in Perinatal Brain Injury
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DOI: 10.3390/biomedicines10061445
Abstract: Perinatal brain injury secondary to hypoxia-ischemia and/or infection/inflammation remains a major cause of disability. Therapeutic hypothermia significantly improves outcomes, but in randomized controlled trials nearly half of infants still died or survived with disability, showing… read more here.
Keywords: connexins pannexins; brain; perinatal brain; brain injury ... See more keywords
The Role of Music Therapy with Infants with Perinatal Brain Injury
Sign Up to like & getrecommendations! Published in 2022 at "Brain Sciences"
DOI: 10.3390/brainsci12050578
Abstract: Perinatal brain injury occurs in 5.14/1000 live births in England. A significant proportion of these injuries result from hypoxic ischaemic encephalopathy (HIE) in term infants and intracranial haemorrhage (IVH) or periventricular leukomalacia (PVL) in preterm… read more here.
Keywords: brain; music therapy; perinatal brain; brain injury ... See more keywords