Perinatal Exposure to Bisphenol A Induces Depressive‐Like Behaviors, ERβ Downregulation, and Dendritic Spine Loss in the Medial Amygdala
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4845
Abstract: Bisphenol A (BPA), a prevalent endocrine‐disrupting chemical used in plastic manufacturing, has been progressively replaced by structural analogs including bisphenol AF (BPAF) and bisphenol S (BPS) due to growing health concerns. However, the neurobehavioral toxicity… read more here.
Keywords: like behaviors; medial amygdala; bpa; bisphenol ... See more keywords
Perinatal exposure to traffic related air pollutants and the risk of infection in the first six months of life: a cohort study from a low-middle income country
Sign Up to like & getrecommendations! Published in 2024 at "International Archives of Occupational and Environmental Health"
DOI: 10.1007/s00420-024-02064-0
Abstract: There is limited study from low-and-middle income countries on the effect of perinatal exposure to air pollution and the risk of infection in infant. We assessed the association between perinatal exposure to traffic related air… read more here.
Keywords: months life; risk; perinatal exposure; respiratory tract ... See more keywords
Perinatal exposure to pesticides alters synaptic plasticity signaling and induces behavioral deficits associated with neurodevelopmental disorders.
Sign Up to like & getrecommendations! Published in 2022 at "Cell biology and toxicology"
DOI: 10.1007/s10565-022-09697-2
Abstract: Increasing evidence from animal and epidemiological studies indicates that perinatal exposure to pesticides cause developmental neurotoxicity and may increase the risk for psychiatric disorders such as autism and intellectual disability. However, the underlying pathogenic mechanisms… read more here.
Keywords: exposure pesticides; associated neurodevelopmental; neurodevelopmental disorders; exposure ... See more keywords
Perinatal exposure to bisphenol A impacts in the mammary gland morphology of adult Mongolian gerbils.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2020.104374
Abstract: The endocrine disruptive effects caused by bisphenol A (BPA) are well known. Despite this, to date, evaluation of its long term effects is limited, meaning that there is still much to be unveiled in terms… read more here.
Keywords: mammary gland; exposure bisphenol; exposure; perinatal exposure ... See more keywords
Influence of perinatal exposure to an endocrine disruptor mixture on the renal microenvironment of aged male rat offspring: histopathological aspects
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174425100172
Abstract: Abstract The developmental origins of health and disease hypothesis suggests that environmental exposures during critical developmental windows increase the risk of disease later in life. Among these, endocrine disruptors (EDs) are particularly concerning due to… read more here.
Keywords: influence perinatal; perinatal exposure; mixture; exposure endocrine ... See more keywords
Early AGEing and metabolic diseases: is perinatal exposure to glycotoxins programming for adult-life metabolic syndrome?
Sign Up to like & getrecommendations! Published in 2020 at "Nutrition reviews"
DOI: 10.1093/nutrit/nuaa074
Abstract: Perinatal early nutritional disorders are critical for the developmental origins of health and disease. Glycotoxins, or advanced glycation end-products, and their precursors such as the methylglyoxal, which are formed endogenously and commonly found in processed… read more here.
Keywords: exposure glycotoxins; early ageing; ageing metabolic; exposure ... See more keywords
Non-alcoholic Fatty Liver Disease Induced by Perinatal Exposure to Bisphenol a Is Associated With Activated mTOR and TLR4/NF-κB Signaling Pathways in Offspring Rats
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2019.00620
Abstract: Accumulating evidence suggests a role of bisphenol A (BPA) in non-alcoholic fatty liver disease (NAFLD), and its mechanism may be related to the up-regulation of lipogenic genes, but the mechanism of BPA induced lipogenic gene… read more here.
Keywords: alcoholic fatty; bpa; non alcoholic; mtor ... See more keywords
Perinatal Exposure to Nicotine Alters Sperm RNA Profiles in Rats
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.893863
Abstract: Perinatal exposure to smoking has been associated with childhood asthma, one of the most common pediatric conditions affecting millions of children globally. Of great interest, this disease phenotype appears heritable as it can persist across… read more here.
Keywords: childhood asthma; exposure smoking; rna profiles; exposure nicotine ... See more keywords
Perinatal exposure to the fungicide ketoconazole alters hypothalamic control of puberty in female rats
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1140886
Abstract: Introduction Estrogenic endocrine disrupting chemicals (EDCs) such as diethylstilbestrol (DES) are known to alter the timing of puberty onset and reproductive function in females. Accumulating evidence suggests that steroid synthesis inhibitors such as ketoconazole (KTZ)… read more here.
Keywords: exposure; female rats; hypothalamic transcriptome; des ktz ... See more keywords
Perinatal Exposure to Phthalates: From Endocrine to Neurodevelopment Effects
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22084063
Abstract: Phthalates, as other endocrine disrupting chemicals (EDCs), may alter the homeostasis and the action of hormones and signaling molecules, causing adverse health outcomes. This is true especially for infants, who are both more exposed and… read more here.
Keywords: phthalates endocrine; exposure; neurodevelopment effects; perinatal exposure ... See more keywords