Perinatal exposure to pesticides alters synaptic plasticity signaling and induces behavioral deficits associated with neurodevelopmental disorders.
Sign Up to like & getrecommendations! Published in 2022 at "Cell biology and toxicology"
DOI: 10.1007/s10565-022-09697-2
Abstract: Increasing evidence from animal and epidemiological studies indicates that perinatal exposure to pesticides cause developmental neurotoxicity and may increase the risk for psychiatric disorders such as autism and intellectual disability. However, the underlying pathogenic mechanisms… read more here.
Keywords: exposure pesticides; associated neurodevelopmental; neurodevelopmental disorders; exposure ... See more keywords
Perinatal exposure to bisphenol A impacts in the mammary gland morphology of adult Mongolian gerbils.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2020.104374
Abstract: The endocrine disruptive effects caused by bisphenol A (BPA) are well known. Despite this, to date, evaluation of its long term effects is limited, meaning that there is still much to be unveiled in terms… read more here.
Keywords: mammary gland; exposure bisphenol; exposure; perinatal exposure ... See more keywords
Early AGEing and metabolic diseases: is perinatal exposure to glycotoxins programming for adult-life metabolic syndrome?
Sign Up to like & getrecommendations! Published in 2020 at "Nutrition reviews"
DOI: 10.1093/nutrit/nuaa074
Abstract: Perinatal early nutritional disorders are critical for the developmental origins of health and disease. Glycotoxins, or advanced glycation end-products, and their precursors such as the methylglyoxal, which are formed endogenously and commonly found in processed… read more here.
Keywords: exposure glycotoxins; early ageing; ageing metabolic; exposure ... See more keywords
Non-alcoholic Fatty Liver Disease Induced by Perinatal Exposure to Bisphenol a Is Associated With Activated mTOR and TLR4/NF-κB Signaling Pathways in Offspring Rats
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2019.00620
Abstract: Accumulating evidence suggests a role of bisphenol A (BPA) in non-alcoholic fatty liver disease (NAFLD), and its mechanism may be related to the up-regulation of lipogenic genes, but the mechanism of BPA induced lipogenic gene… read more here.
Keywords: alcoholic fatty; bpa; non alcoholic; mtor ... See more keywords
Perinatal Exposure to Nicotine Alters Sperm RNA Profiles in Rats
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.893863
Abstract: Perinatal exposure to smoking has been associated with childhood asthma, one of the most common pediatric conditions affecting millions of children globally. Of great interest, this disease phenotype appears heritable as it can persist across… read more here.
Keywords: childhood asthma; exposure smoking; rna profiles; exposure nicotine ... See more keywords
Perinatal exposure to the fungicide ketoconazole alters hypothalamic control of puberty in female rats
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1140886
Abstract: Introduction Estrogenic endocrine disrupting chemicals (EDCs) such as diethylstilbestrol (DES) are known to alter the timing of puberty onset and reproductive function in females. Accumulating evidence suggests that steroid synthesis inhibitors such as ketoconazole (KTZ)… read more here.
Keywords: exposure; female rats; hypothalamic transcriptome; des ktz ... See more keywords
Perinatal Exposure to Phthalates: From Endocrine to Neurodevelopment Effects
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22084063
Abstract: Phthalates, as other endocrine disrupting chemicals (EDCs), may alter the homeostasis and the action of hormones and signaling molecules, causing adverse health outcomes. This is true especially for infants, who are both more exposed and… read more here.
Keywords: phthalates endocrine; exposure; neurodevelopment effects; perinatal exposure ... See more keywords