Permeability of the Perindopril Arginine under In Vitro Conditions across Caco-2 Monolayer and Biomimetic Phospholipid Membrane
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27072232
Abstract: Perindopril arginine (PA) as an angiotensin-converting enzyme (ACE) inhibitor is widely used in cardiovascular diseases, especially in systemic hypertension and heart failure. Although the pharmacokinetics of PA are well documented, there is no available detailed… read more here.
Keywords: across caco; vitro conditions; phospholipid membrane; membrane ... See more keywords
Method development and validation of HPLC tandem/mass spectrometry for quantification of perindopril arginine and amlodipine besylate combination in bulk and pharmaceutical formulations
Sign Up to like & getrecommendations! Published in 2017 at "Research in Pharmaceutical Sciences"
DOI: 10.4103/1735-5362.212048
Abstract: A well-characterized and fully validated ultra-high performance liquid chromatography-electrospray ionization-tandem mass spectrometric (UHPLC-ESI-MS/MS) method was developed to reliably analyze combination of perindopril arginine and amlodipine besylate in bulk and tablet formulations. The chromatographic separation was… read more here.
Keywords: perindopril arginine; tandem mass; amlodipine besylate; arginine amlodipine ... See more keywords