Lymphovascular or perineural invasion is associated with lymph node metastasis and survival outcomes in patients with gastric cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5701
Abstract: Lymphovascular invasion (LVI) and perineural invasion (PNI) are associated with poorer prognosis in several human malignancies, but their significance in gastric cancer (GC) remains to be clearly defined. Our study aimed to investigate the prognostic… read more here.
Keywords: invasion; gastric cancer; lymphovascular perineural; cancer ... See more keywords
Perineural invasion is related to p38 mitogen‐activated protein kinase pathway activation and promotes tumor growth and chemoresistance in pancreatic cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28457
Abstract: Metastasis is a key component of cancer progression and is strongly associated with poor prognosis. Perineural invasion is thought to be related to pain, tumor recurrence, and other conditions. However, the exact molecular mechanism is… read more here.
Keywords: perineural invasion; pancreatic cancer; p38 mitogen; cancer ... See more keywords
Downregulation of MMP1 functions in preventing perineural invasion of pancreatic cancer through blocking the NT‐3/TrkC signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24719
Abstract: Pancreatic cancer (PC) is a fatal malignancy that frequently involves perineural invasion (PNI). This study aims to investigate the function and underlying mechanisms of matrix metalloproteinase‐1 (MMP1) in PNI of PC. read more here.
Keywords: pancreatic cancer; downregulation mmp1; perineural invasion;
Pretreatment MR-based radiomics nomogram as potential imaging biomarker for individualized assessment of perineural invasion status in rectal cancer
Sign Up to like & getrecommendations! Published in 2020 at "Abdominal Radiology"
DOI: 10.1007/s00261-020-02710-4
Abstract: To investigate whether pretreatment magnetic resonance (MR)-based radiomics nomogram can individualize prediction of perineural invasion (PNI) status in rectal cancer (RC). A total of 122 RC patients with pathologically confirmed were classified as training cohort… read more here.
Keywords: status; perineural invasion; based radiomics; cohort ... See more keywords
The value of 18F-FDG PET/CT-based radiomics in predicting perineural invasion and outcome in non-metastatic colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Abdominal Radiology"
DOI: 10.1007/s00261-022-03453-0
Abstract: Perineural invasion (PNI) has been recognized as an important prognosis factor in patients with colorectal cancer (CRC). The purpose of this retrospective study was to investigate the value of 18F-FDG PET/CT-based radiomics integrating clinical information,… read more here.
Keywords: non metastatic; metastatic crc; perineural invasion; pet ... See more keywords
Perineural invasion and number of retrieved lymph nodes are prognostic factors for T2N0 colon cancer
Sign Up to like & getrecommendations! Published in 2021 at "Langenbeck's Archives of Surgery"
DOI: 10.1007/s00423-021-02172-2
Abstract: The prognosis of pathological T2N0 colon cancer has not been adequately investigated. This study aimed to determine the prognostic factors for pathological T2N0 colon cancer by comparing it with those for pathological T3N0 colon cancer.… read more here.
Keywords: perineural invasion; prognostic factors; colon; colon cancer ... See more keywords
Interobserver reproducibility of perineural invasion of prostatic adenocarcinoma in needle biopsies
Sign Up to like & getrecommendations! Published in 2021 at "Virchows Archiv"
DOI: 10.1007/s00428-021-03039-z
Abstract: Numerous studies have shown a correlation between perineural invasion (PNI) in prostate biopsies and outcome. The reporting of PNI varies widely in the literature. While the interobserver variability of prostate cancer grading has been studied… read more here.
Keywords: interobserver reproducibility; pni; perineural invasion; pathology ... See more keywords
Detection of perineural invasion in prostate needle biopsies with deep neural networks
Sign Up to like & getrecommendations! Published in 2022 at "Virchows Archiv"
DOI: 10.1007/s00428-022-03326-3
Abstract: The presence of perineural invasion (PNI) by carcinoma in prostate biopsies has been shown to be associated with poor prognosis. The assessment and quantification of PNI are, however, labor intensive. To aid pathologists in this… read more here.
Keywords: biopsy; prostate; deep neural; neural networks ... See more keywords
A novel histologic grading system based on lymphovascular invasion, perineural invasion, and tumor budding in colorectal cancer
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-018-2804-4
Abstract: PurposeThis study aimed to evaluate the prognostic significance of lymphovascular (LVI), perineural invasion (PNI), and tumor budding positivity in patients with colorectal cancer.MethodsFrom January 2008 to December 2011, 3707 consecutive patients who underwent curative surgery… read more here.
Keywords: perineural invasion; colorectal cancer; cancer; tumor budding ... See more keywords
New method for the assessment of perineural invasion from perihilar cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Surgery Today"
DOI: 10.1007/s00595-020-02071-x
Abstract: Purpose Perineural invasion (PN) is often found in perihilar cholangiocarcinoma. New procedure was developed to assess PN around the right hepatic artery (RHA) using dual-energy computed tomography (DECT). Methods Thirty patients with perihilar cholangiocarcinoma who… read more here.
Keywords: number pal; perineural invasion; perihilar cholangiocarcinoma; pal ... See more keywords
Does preoperative stent positioning in obstructive left sided colon cancer increase the risk of perineural invasion?
Sign Up to like & getrecommendations! Published in 2021 at "Updates in Surgery"
DOI: 10.1007/s13304-020-00962-9
Abstract: Colonic stenting as a bridge to surgery has been shown to be a safe and effective treatment for left-sided malignant colonic obstruction depending on local expertise. However, concerns still exist regarding its oncological safety. In… read more here.
Keywords: invasion; colon cancer; left sided; perineural invasion ... See more keywords