Perineuronal nets and subtypes of GABAergic cells differentiate auditory and multisensory nuclei in the intercollicular area of the midbrain
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24926
Abstract: The intercollicular region, which lies between the inferior and superior colliculi in the midbrain, contains neurons that respond to auditory, visual, and somatosensory stimuli. Golgi studies have been used to parse this region into three… read more here.
Keywords: gabaergic cells; nuclei intercollicular; intercollicular nuclei; subtypes gabaergic ... See more keywords
Development of parvalbumin neurons and perineuronal nets in the visual cortex of normal and dark‐exposed cats
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25127
Abstract: During development, the visual system maintains a high capacity for modification by expressing characteristics permissive for plasticity, enabling neural circuits to be refined by visual experience to achieve their mature form. This period is followed… read more here.
Keywords: parvalbumin; plasticity; development; perineuronal nets ... See more keywords
Sexually dimorphic perineuronal nets in the rodent and primate reproductive circuit
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25167
Abstract: Perineuronal nets are extracellular glycoprotein structures that have been found on some neurons in the central nervous system and that have been shown to regulate their structural plasticity. Until now work on perineuronal nets has… read more here.
Keywords: rodent primate; dimorphic perineuronal; nets rodent; sexually dimorphic ... See more keywords
Elimination of perineuronal nets in CA1 disrupts GABA release and long-term contextual fear memory retention.
Sign Up to like & getrecommendations! Published in 2023 at "Hippocampus"
DOI: 10.1002/hipo.23503
Abstract: Perineuronal nets (PNNs) which mostly surround the parvalbumin (PV) neurons, have been shown to play critical roles in neural plasticity. Recently, PNNs have been shown to regulate fear-associated memory, but the molecular mechanism is still… read more here.
Keywords: long term; term contextual; perineuronal nets; fear memory ... See more keywords
Auditory temporal acuity improves with age in the male mouse auditory thalamus: A role for perineuronal nets?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24537
Abstract: The ability to perceive and interpret environmental sound accurately is conserved across many species and is fundamental for understanding communication via vocalizations. Auditory acuity and temporally controlled neuronal firing underpin this ability. Deterioration in neuronal… read more here.
Keywords: acuity; age; neuronal firing; auditory thalamus ... See more keywords
Chronic Toxoplasma gondii infection contributes to decreasing of perineuronal nets surrounding neurons in the Corpus striatum of mice
Sign Up to like & getrecommendations! Published in 2020 at "Parasitology Research"
DOI: 10.1007/s00436-020-06674-8
Abstract: Recent advances in chronic toxoplasmosis understanding became the focus of discussion about behavioral abnormalities, which could be explained by cyst location and neuronal impairment in specific brain areas. Perineuronal nets (PNNs) are specialized extracellular matrices… read more here.
Keywords: toxoplasma gondii; mice; perineuronal nets; infection ... See more keywords
Enzymatic Degradation of Cortical Perineuronal Nets Reverses GABAergic Interneuron Maturation.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular neurobiology"
DOI: 10.1007/s12035-022-02772-z
Abstract: Perineuronal nets (PNNs) are specialised extracellular matrix structures which preferentially enwrap fast-spiking (FS) parvalbumin interneurons and have diverse roles in the cortex. PNN maturation coincides with closure of the critical period of cortical plasticity. We… read more here.
Keywords: perineuronal nets; chabc; maturation; enzymatic degradation ... See more keywords
Primary cilia are required for the persistence of memory and stabilization of perineuronal nets
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DOI: 10.1016/j.isci.2021.102617
Abstract: Summary It is well established that the formation of episodic memories requires multiple hippocampal mechanisms operating on different time scales. Early mechanisms of memory formation (synaptic consolidation) have been extensively characterized. However, delayed mechanisms, which… read more here.
Keywords: required persistence; primary cilia; primary cilium; memory ... See more keywords
A lack of GluN2A-containing NMDA receptors confers a vulnerability to redox dysregulation: Consequences on parvalbumin interneurons, and their perineuronal nets
Sign Up to like & getrecommendations! Published in 2018 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2017.10.006
Abstract: The GluN2A subunit of NMDA receptors (NMDARs) plays a critical role during postnatal brain development as its expression increases while Glun2B expression decreases. Mutations and polymorphisms in GRIN2A gene, coding for GluN2A, are linked to… read more here.
Keywords: parvalbumin interneurons; glun2a containing; lack glun2a; glun2a ... See more keywords
Age-dependent and region-specific alteration of parvalbumin neurons and perineuronal nets in the mouse cerebral cortex
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DOI: 10.1016/j.neuint.2017.11.001
Abstract: &NA; Cognitive function declines with age. Such function depends on &ggr;‐oscillation in the frontal cortex. Pyramidal neurons, and the parvalbumin‐expressing interneurons (PV neurons) that control them, are important for the generation of &ggr;‐oscillation. The mechanism… read more here.
Keywords: cortex; cerebral cortex; age; density ... See more keywords
Precocious deposition of perineuronal nets on Parvalbumin inhibitory neurons transplanted into adult visual cortex
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DOI: 10.1038/s41598-018-25735-8
Abstract: The end of the critical period for primary visual cortex (V1) coincides with the deposition of perineuronal nets (PNN) onto Parvalbumin (PV) inhibitory neurons. Recently, we found that transplantation of embryonic inhibitory neurons into adult… read more here.
Keywords: deposition; inhibitory neurons; deposition perineuronal; precocious deposition ... See more keywords