A dominant negative mitofusin causes mitochondrial perinuclear clusters because of aberrant tethering
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DOI: 10.26508/lsa.202101305
Abstract: Our analysis of a CMT2A-associated mitofusin variant reveals that aberrant mitochondrial tethering results in perinuclear clusters and that conformational dynamics in Hinge 2 are required to progress from membrane tethering to membrane fusion. In vertebrates,… read more here.
Keywords: mitofusin; fusion; membrane fusion; mitochondrial perinuclear ... See more keywords