Rapid synaptic and gamma rhythm signature of mouse critical period plasticity.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2123182120
Abstract: Early-life experience enduringly sculpts thalamocortical (TC) axons and sensory processing. Here, we identify the very first synaptic targets that initiate critical period plasticity, heralded by altered cortical oscillations. Monocular deprivation (MD) acutely induced a transient… read more here.
Keywords: critical period; period; rhythm; gamma ... See more keywords
A synapse-specific refractory period for plasticity at individual dendritic spines
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2410433122
Abstract: Significance A refractory period in which newly modified synaptic connections are unable to undergo further plasticity is a proposed mechanism through which newly formed memories can be preserved at the synaptic level while brain plasticity… read more here.
Keywords: synapse specific; plasticity individual; plasticity; period plasticity ... See more keywords
Silent Synapse-Based Mechanisms of Critical Period Plasticity
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2020.00213
Abstract: Critical periods are postnatal, restricted time windows of heightened plasticity in cortical neural networks, during which experience refines principal neuron wiring configurations. Here, we propose a model with two distinct types of synapses, innate synapses… read more here.
Keywords: critical period; period plasticity; gestalt; gestalt synapses ... See more keywords