Increased Viability of Sugar Transport-Deficient Mutant of the Periodontal Pathogen, Aggregatibacter actinomycetemcomitans
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DOI: 10.1007/s00284-018-1545-6
Abstract: The periodontal pathogen, Aggregatibacter actinomycetemcomitans is extremely sensitive to even a mildly acidic pH resulting from metabolic acids secreted during growth, losing viability rapidly as the pH goes below 6.0. Cells grown at high glucose… read more here.
Keywords: aggregatibacter actinomycetemcomitans; viability; pathogen aggregatibacter; sugar transport ... See more keywords
Oral application of a periodontal pathogen impacts SerpinE1 expression and pancreatic islet architecture in prediabetes
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DOI: 10.1111/jre.12474
Abstract: BACKGROUND AND OBJECTIVES Epidemiological studies suggest a close association between periodontitis and prediabetes/insulin resistance (IR) but whether periodontitis causes prediabetes in humans is not known. Using various animal models, we have recently established that periodontitis… read more here.
Keywords: oral application; periodontal pathogen; serpine1; application periodontal ... See more keywords
In Vitro and In Vivo Activity of Peptidomimetic Compounds That Target the Periodontal Pathogen Porphyromonas gingivalis
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DOI: 10.1128/aac.00400-18
Abstract: ABSTRACT The interaction of the periodontal pathogen Porphyromonas gingivalis with oral streptococci is important for initial colonization of the oral cavity by P. gingivalis and is mediated by a discrete motif of the streptococcal antigen… read more here.
Keywords: vivo activity; vitro vivo; pathogen porphyromonas; porphyromonas gingivalis ... See more keywords
Chronic Periodontal Disease, Periodontal Pathogen Colonization, and Increased Risk of Precancerous Gastric Lesions
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DOI: 10.1902/jop.2017.160829
Abstract: BACKGROUND This study assesses the association between periodontal pathogen colonization and the potential risk of developing precancerous lesions of gastric cancer (PLGC) in a clinical setting. METHODS Included were 35 newly diagnosed patients with PLGC… read more here.
Keywords: risk; increased risk; colonization; pathogen colonization ... See more keywords
Microbial Screening Reveals Oral Site-Specific Locations of the Periodontal Pathogen Selenomonas noxia.
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DOI: 10.3390/cimb43010029
Abstract: INTRODUCTION Selenomonas noxia (SN) is an important periodontal pathogen, associated with gingivitis and periodontitis. Many studies have found associations between SN and indicators of poor health outcomes, such as smoking, low socioeconomic status and obesity.… read more here.
Keywords: selenomonas noxia; site specific; site; oral site ... See more keywords