Engineered Delivery of Dental Stem‐Cell‐Derived Extracellular Vesicles for Periodontal Tissue Regeneration
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102593
Abstract: Periodontal disease begins as an inflammatory response to a bacterial biofilm deposited around the teeth, which over time leads to the destruction of tooth‐supporting structures and consequently tooth loss. Conventional treatment strategies show limited efficacy… read more here.
Keywords: regeneration; extracellular vesicles; periodontal tissue; stem ... See more keywords
Nuclear factor-kappa B (NF-κB) decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid (PLGA) nanospheres promote periodontal tissue healing after tooth replantation in rats.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of periodontology"
DOI: 10.1002/jper.21-0134
Abstract: BACKGROUND Excessive inflammation in the periodontal tissue after tooth replantation can lead to inflammatory root resorption and interrupt periodontal tissue regeneration. We tested the hypothesis that NF-κB decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid nanospheres (NF-PLGA) inhibit… read more here.
Keywords: tooth replantation; plga; periodontal tissue; factor ... See more keywords
Clumps of mesenchymal stem cells/extracellular matrix complexes directly reconstruct the functional periodontal tissue in a rat periodontal defect model
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.3343
Abstract: Periodontitis is an inflammatory disease characterized by tooth‐supporting periodontal tissue destruction, including the cementum, periodontal ligament, and alveolar bone. To regenerate the damaged periodontal tissue, mesenchymal stem cells (MSCs) have attracted much scientific and medical… read more here.
Keywords: rat periodontal; defect model; periodontal tissue; mscs ... See more keywords
Electrospun Polysaccharides for Periodontal Tissue Engineering: A Review of Recent Advances and Future Perspectives.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of biomedical engineering"
DOI: 10.1007/s10439-022-02952-x
Abstract: Periodontitis is the leading cause of tooth loss among the adult population. Indeed, conventional treatment modalities have specific challenges such as scar tissue infiltration, the formation of long epithelium junctions, and aesthetic limitations. Therefore, the… read more here.
Keywords: tissue engineering; electrospun polysaccharides; future perspectives; periodontal tissue ... See more keywords
Dental tissue-derived stem cell sheet biotechnology for periodontal tissue regeneration: A systematic review.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2021.105182
Abstract: OBJECTIVE This study aimed to conduct a systematic review of the use of a cell sheet formed by mesenchymal stem cells derived from dental tissues (ddMSCs) for periodontal tissue regeneration in animal models in comparison… read more here.
Keywords: cell sheet; periodontal tissue; tissue regeneration; tissue ... See more keywords
Nanocarrier-Assisted Delivery of Metformin Boosts Remodeling of Diabetic Periodontal Tissue via Cellular Exocytosis-Mediated Regulation of Endoplasmic Reticulum Homeostasis.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.2c08146
Abstract: Endoplasmic reticulum (ER) dysfunction is a potential contributor to the impaired repair capacity of periodontal tissue in diabetes mellitus (DM) patients. Restoring ER homeostasis is thus critical for successful regenerative therapy of diabetic periodontal tissue.… read more here.
Keywords: diabetic periodontal; remodeling diabetic; periodontal tissue; metformin ... See more keywords
Hierarchically Patterned Polydopamine-Containing Membranes for Periodontal Tissue Engineering.
Sign Up to like & getrecommendations! Published in 2019 at "ACS nano"
DOI: 10.1021/acsnano.8b09623
Abstract: Periodontitis is a common chronic inflammatory disease that affects tooth-supporting tissues. We engineer a multifunctional periodontal membrane for the guided tissue regeneration of lost periodontal tissues. The major drawback of current periodontal membranes is the… read more here.
Keywords: periodontal tissue; regeneration; tissue; polydopamine ... See more keywords
A new approach to transfect NF-κB decoy oligodeoxynucleotides into the periodontal tissue using the ultrasound-microbubble method
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Oral Science"
DOI: 10.1038/ijos.2017.10
Abstract: The objective of this study is to investigate the effect of the ultrasound-microbubble technique in nuclear factor kappa B (NF-κB) decoy oligodeoxynucleotide (ODN) transfection in the gingival tissue in mice. The 6-FAM-labeled scrambled decoy ODN… read more here.
Keywords: ultrasound microbubble; periodontal tissue; hum; tissue ... See more keywords
Immunomodulatory nanotherapeutic approaches for periodontal tissue regeneration.
Sign Up to like & getrecommendations! Published in 2023 at "Nanoscale"
DOI: 10.1039/d2nr06149j
Abstract: Periodontitis is an infection-induced inflammatory disease characterized by progressive destruction of tooth supporting tissues, which, if left untreated, can result in tooth loss. The destruction of periodontal tissues is primarily caused by an imbalance between… read more here.
Keywords: regeneration; nanotherapeutic approaches; periodontal tissue; immunomodulatory nanotherapeutic ... See more keywords
Oral supplementation with p-coumaric acid protects mice against diabetes-associated spontaneous destruction of periodontal tissue.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of periodontal research"
DOI: 10.1111/jre.12678
Abstract: OBJECTIVE Dietary bioactive materials having anti-inflammatory and antioxidant potentials are able to inhibit diabetes-associated periodontal complications. Although numerous studies indicate that administration of p-coumaric acid (p-CA) ameliorates diabetes and diabetes-related complications, the roles of p-CA… read more here.
Keywords: stz; periodontal tissue; destruction; group ... See more keywords
The Role of Proteinase-Activated Receptors 1 and 2 in the Regulation of Periodontal Tissue Metabolism and Disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Immunology Research"
DOI: 10.1155/2017/5193572
Abstract: Proteinase-activated receptors 1 (PAR1) and 2 (PAR2) are the most highly expressed members of the PAR family in the periodontium. These receptors regulate periodontal inflammatory and repair processes through their activation by endogenous and bacterial… read more here.
Keywords: tissue metabolism; periodontal tissue; proteinase; activated receptors ... See more keywords