Articles with "peripheral cell" as a keyword



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A case of peripheral T‐cell lymphoma, NOS, mimicking acute monocytic leukemia

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Published in 2022 at "American Journal of Hematology"

DOI: 10.1002/ajh.26476

Abstract: IMAGE 1 Upper panels: Intermediate to large-sized neoplastic cells present in the peripheral blood smear that were thought to be monocytic blasts on preliminary examination at an outside hospital (Wright Giemsa stain, original magnification 500).… read more here.

Keywords: case peripheral; cell; cell lymphoma; peripheral cell ... See more keywords
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Pitfalls and major issues in the histologic diagnosis of peripheral T‐cell lymphomas: results of the central review of 573 cases from the T‐Cell Project, an international, cooperative study

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Published in 2017 at "Hematological Oncology"

DOI: 10.1002/hon.2316

Abstract: Peripheral T‐cell lymphomas (PTCLs) comprise a heterogeneous group of neoplasms that are derived from post‐thymic lymphoid cells at different stages of differentiation with different morphological patterns, phenotypes and clinical presentations. PTCLs are highly diverse, reflecting… read more here.

Keywords: cell lymphomas; cell project; study; cell ... See more keywords
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Serum concentrations of l‐kynurenine predict clinical outcomes of patients with peripheral T‐cell lymphoma, not otherwise specified

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Published in 2017 at "Hematological Oncology"

DOI: 10.1002/hon.2318

Abstract: Indoleamine 2,3‐dioxygenase exerts intense immunomodulatory effects due to enzymatic activities that catalyze the breakdown of the essential amino acid l‐tryptophan. The activity of indoleamine 2,3‐dioxygenase can be estimated by measuring serum l‐kynurenine concentrations. Here, we… read more here.

Keywords: lymphoma otherwise; serum; peripheral cell; otherwise specified ... See more keywords
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OUTCOME OF PATIENTS WITH RELAPSED AND REFRACTORY PERIPHERAL T CELL LYMPHOMA INTENDED FOR STEM CELL TRANSPLANT

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Published in 2017 at "Hematological Oncology"

DOI: 10.1002/hon.2438_104

Abstract: OUTCOME OF PATIENTS WITH RELAPSED AND REFRACTORY PERIPHERAL T CELL LYMPHOMA INTENDED FOR STEM CELL TRANSPLANT S. Parkin* | S. Wong | J.M. Connors | L. Sehn | D. Villa | A. Gerrie | R.… read more here.

Keywords: relapsed refractory; refractory peripheral; outcome patients; patients relapsed ... See more keywords
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Dynamics of peripheral T cell clones during PD-1 blockade in non-small cell lung cancer

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Published in 2020 at "Cancer Immunology, Immunotherapy"

DOI: 10.1007/s00262-020-02642-4

Abstract: Understanding of the functional states and clonal dynamics of T cells after immune checkpoint blockade (ICB) is valuable for improving these therapeutic strategies. Here we performed Smart-seq2 single-cell RNA sequencing (scRNA-seq) analysis on 3,110 peripheral… read more here.

Keywords: cell clones; small cell; non small; cancer ... See more keywords
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T-cell receptor-silent peripheral T-cell lymphoma complicated with hemophagocytic lymphohystiocytosis

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Published in 2021 at "Annals of Hematology"

DOI: 10.1007/s00277-021-04628-3

Abstract: T-cell receptor (TCR) is associated with diverse antigen recognition in T-cells [1]. Peripheral T-cell lymphomas (PTCLs) are the neoplastic counterpart of postthymic T-cells [2] and usually express either αβ-TCR or γδ-TCR. However, rare cases of… read more here.

Keywords: cell receptor; cell; peripheral cell; tcr silent ... See more keywords
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Peripheral T cell lymphoma of the nasopharynx with expansion of EBV-positive B cells masquerading as an extranodal NK/T cell lymphoma, nasal type

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Published in 2022 at "Virchows Archiv"

DOI: 10.1007/s00428-021-03240-0

Abstract: Epstein-Barr virus-infected B cells are found at high frequency in peripheral T cell lymphoma. Herein, we report a case involving excessive EBV-positive B cells accompanying peripheral T cell lymphoma, not otherwise specified in the nasopharynx… read more here.

Keywords: peripheral cell; ebv positive; cell; cell lymphoma ... See more keywords
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Hematopoietic Cell Transplantation and Adoptive Cell Therapy in Peripheral T Cell Lymphoma

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Published in 2020 at "Current Hematologic Malignancy Reports"

DOI: 10.1007/s11899-020-00590-5

Abstract: Purpose of Review Peripheral T cell lymphomas (PTCLs) are a heterogeneous group of diseases and represent approximately 10–15% of all non-Hodgkin lymphomas. Multiagent chemotherapy with a CHOP (cyclophosphamide, adriamycin, vincristine, prednisone)-like regimen is the current… read more here.

Keywords: treatment; ptcl; hematopoietic cell; therapy ... See more keywords
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Dock5 controls the peripheral B cell differentiation via regulating BCR signaling and actin reorganization.

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Published in 2019 at "Cellular immunology"

DOI: 10.1016/j.cellimm.2019.01.001

Abstract: As an atypical guanine nucleotide exchange factor (GEF), Dock5 has been extensively studied in cellular functions. However, the role of Dock5 on B-cell immunity still remain elusive. In this study, we generated a Dock5 knockout… read more here.

Keywords: differentiation; dock5; bcr signaling; cell ... See more keywords
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Peripheral T-cell lymphomas: Focusing on novel agents in relapsed and refractory disease.

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Published in 2017 at "Cancer treatment reviews"

DOI: 10.1016/j.ctrv.2017.09.002

Abstract: Patients with relapsed or refractory peripheral T-cell lymphoma display a dismal prognosis and their therapy represents an unmet medical need, as the best treatment strategy is yet to be determined. Exciting data on novel targeted… read more here.

Keywords: relapsed refractory; cell lymphomas; lymphomas focusing; focusing novel ... See more keywords
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Peripheral T-Cell Lymphoma: Moving Toward Targeted Therapies.

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Published in 2019 at "Hematology/oncology clinics of North America"

DOI: 10.1016/j.hoc.2019.04.002

Abstract: Therapeutic advances for peripheral T-cell non-Hodgkin lymphoma (PTCL) have lagged behind their B-cell NHL counterparts in part because novel agents to treat PTCL have been developed empirically. The recent clinical success of brentuximab-vedotin suggests that… read more here.

Keywords: cell lymphoma; peripheral cell; cell; toward targeted ... See more keywords