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   Articles with "peripheral cells" as a keyword



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The role of Syk in peripheral T cells.

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recommendations! Published in 2018 at "Clinical immunology"

DOI: 10.1016/j.clim.2018.04.007

Abstract: The aim of this study was to understand how Syk affects peripheral T cell function. T cells from Syk-/- chimeric mice and DR1 Sykfl/fl CD4cre conditional mice gave strong CD3-induced Th1, Th2, and Th17 cytokine… read more here.

Keywords: peripheral cells; syk peripheral; role syk; syk ... See more keywords

Analysis of coding and non-coding transcriptome of peripheral B cells reveals an altered interferon response factor (IRF)-1 pathway in multiple sclerosis patients

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recommendations! Published in 2018 at "Journal of Neuroimmunology"

DOI: 10.1016/j.jneuroim.2018.09.005

Abstract: Several evidences emphasize B-cell pathogenic roles in multiple sclerosis (MS). We performed transcriptome analyses on peripheral B cells from therapy-free patients and age/sex-matched controls. Down-regulation of two transcripts (interferon response factor 1-IRF1, and C-X-C motif… read more here.

Keywords: interferon response; multiple sclerosis; response factor; peripheral cells ... See more keywords

Glycodelin regulates the numbers and function of peripheral natural killer cells.

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recommendations! Published in 2019 at "Journal of reproductive immunology"

DOI: 10.1016/j.jri.2019.102625

Abstract: Natural killer (NK) cells comprise of ∼70% of the immune cell population in the maternal decidua and ∼15% of the mononuclear cells in the peripheral blood. The decidual NK cells capable of producing high levels… read more here.

Keywords: peripheral cells; natural killer; effect; glycodelin ... See more keywords

p‐Cresyl sulfate decreases peripheral B cells in mice with adenine‐induced renal dysfunction

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recommendations! Published in 2018 at "Toxicology and Applied Pharmacology"

DOI: 10.1016/j.taap.2018.01.025

Abstract: ABSTRACT Infection is a major cause of mortality in chronic kidney disease (CKD) patients. Although immune dysfunction is a risk factor for infection in CKD patients, its causes are not fully elucidated. In the present… read more here.

Keywords: renal dysfunction; peripheral cells; dysfunction; cell progenitors ... See more keywords

Single-Cell Multiomics Identifies Glycan Epitope LacNAc as a Potential Cell-Surface Effector Marker of Peripheral T Cells in Bladder Cancer Patients

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recommendations! Published in 2024 at "ACS Chemical Biology"

DOI: 10.1021/acschembio.4c00635

Abstract: Cancer is a systemic disease continuously monitored and responded to by the human global immune system. Peripheral blood immune cells, integral to this surveillance, exhibit variable phenotypes during tumor progression. Glycosylation, as one of the… read more here.

Keywords: cancer; single cell; cancer patients; peripheral cells ... See more keywords

Proteomic signatures and mitochondrial dysfunctions in peripheral T cells reveal novel ınsights into Alzheimer’s disease

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-22783-9

Abstract: Alzheimer’s disease (AD) exhibits progressive cognitive decline and recent scientific studies hint to the peripheral immune system as a contributor. In this study, we isolated peripheral immune cells including CD4 + and CD8 + T cells, CD14 + monocytes and CD19 + B… read more here.

Keywords: alzheimer disease; disease; cd8 cells; peripheral cells ... See more keywords

Aberrant Lower CD6 Expression on Peripheral B Cells Associated With Liver/Kidney Injury and Autoantibody Production of Systemic Lupus Erythematosus Patients

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recommendations! Published in 2025 at "Scandinavian Journal of Immunology"

DOI: 10.1111/sji.70018

Abstract: Systemic lupus erythematosus (SLE) is a multi‐system autoimmune disease characterised by aberrant activation and differentiation of autoreactive T and B cells, as well as the overproduction of autoantibodies. CD6, a cell‐surface glycoprotein, regulates lymphocyte activation,… read more here.

Keywords: cd6 expression; lupus; expression peripheral; peripheral cells ... See more keywords
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Impact of the body mass index on perioperative immunological disturbances in patients with hip and knee arthroplasty

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recommendations! Published in 2017 at "Journal of Orthopaedic Surgery and Research"

DOI: 10.1186/s13018-017-0557-4

Abstract: BackgroundObesity increases the risk for knee and hip joint implantation and negatively contributes to wound healing. In this study, in 52 patients undergoing hip and knee arthroplasty the amount of peripheral immune effector cells pre-… read more here.

Keywords: peripheral cells; bmi; immune effector; knee arthroplasty ... See more keywords

Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells

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recommendations! Published in 2024 at "eLife"

DOI: 10.7554/elife.76940

Abstract: The fate of developing T cells is determined by the strength of T cell receptor (TCR) signal they receive in the thymus. This process is finely regulated through the tuning of positive and negative regulators… read more here.

Keywords: tcr signal; peripheral cells; thymocytes peripheral; fam49b dampens ... See more keywords