Identification of T Peripheral Helper (Tph) Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1736-6_6
Abstract: T peripheral helper (Tph) cells represent a T cell population that stimulates B cell responses within peripheral tissues. Like T follicular helper (Tfh) cells, PD-1hi CXCR5- CD4+ Tph cells produce IL-21 and CXCL13, yet these… read more here.
Keywords: tph; peripheral helper; tph cells; tfh cells ... See more keywords
Expanded circulating peripheral helper T cells in primary biliary cholangitis: Tph cells in PBC.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular immunology"
DOI: 10.1016/j.molimm.2020.09.007
Abstract: BACKGROUND Peripheral helper T (TPH) cells, a recently defined subset of Th cells, promote B cell differentiation and antibody production in inflamed tissues. This study investigated whether circulating TPH cells are associated with primary biliary… read more here.
Keywords: tph; peripheral helper; tph cells; pbc ... See more keywords
Competitive Binding of Transcription Factors Underlies Flexibility of T Peripheral Helper Cells and T Follicular Helper Cells in SLE.
Sign Up to like & getrecommendations! Published in 2022 at "Rheumatology"
DOI: 10.1093/rheumatology/keac112
Abstract: OBJECTIVE Peripheral helper T (Tph) cells interact with B cells and promote immune responses at sites of ectopic lymphoid structures (ELSs). To assess the characteristics of Tph cells, we investigated the phenotype of T helper… read more here.
Keywords: tph cells; peripheral helper; helper; helper cells ... See more keywords
Peripheral Helper T Cell Responses in Human Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.946786
Abstract: A series of rheumatoid arthritis (RA) studies established a PD-1hiCXCR5-CD4+ T-cell subset that was coined peripheral helper T (Tph) cells. CXCL13 production is a key feature of Tph cells and may contribute to the formation… read more here.
Keywords: human diseases; cell; peripheral helper; tph cells ... See more keywords