Long‐term peripheral immune cell profiling reveals further targets of oral cladribine in MS
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51206
Abstract: To expand the knowledge about the immunological consequences of cladribine (CLAD), a pulsed immune reconstitution therapy approved for active multiple sclerosis (MS), beyond the known short‐term effects on peripheral immune cell subsets. read more here.
Keywords: immune cell; peripheral immune; long term;
The role of peripheral immune cells in the CNS in steady state and disease
Sign Up to like & getrecommendations! Published in 2017 at "Nature Neuroscience"
DOI: 10.1038/nn.4475
Abstract: The CNS is protected by the immune system, including cells that reside directly within the CNS and help to ensure proper neural function, as well as cells that traffic into the CNS with disease. The… read more here.
Keywords: cells cns; immune cells; peripheral immune; disease ... See more keywords
The relationship between peripheral immune response and disease severity in SARS‐CoV‐2‐infected subjects: A cross‐sectional study
Sign Up to like & getrecommendations! Published in 2022 at "Immunology"
DOI: 10.1111/imm.13457
Abstract: Coronavirus disease 2019 (COVID‐19) is a respiratory infection caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and marked by an intense inflammatory response and immune dysregulation in the most severe cases. In order to… read more here.
Keywords: relationship peripheral; peripheral immune; disease; response ... See more keywords
The peripheral immune response of mice infected with a neuropathogenic schistosome
Sign Up to like & getrecommendations! Published in 2020 at "Parasite Immunology"
DOI: 10.1111/pim.12710
Abstract: Trichobilharzia regenti (Schistosomatidae) percutaneously infects birds and mammals and invades their central nervous system (CNS). Here, we characterized the peripheral immune response of infected mice and showed how it was influenced by the parasite‐induced inflammation… read more here.
Keywords: peripheral immune; response; immune response; mice infected ... See more keywords
PAVLOVIAN CONDITIONING OF IMMUNOLOGICAL AND NEUROENDOCRINE FUNCTIONS.
Sign Up to like & getrecommendations! Published in 2019 at "Physiological reviews"
DOI: 10.1152/physrev.00033.2018
Abstract: The phenomenon of behaviorally conditioned immunological and neuroendocrine responses has been investigated for the past 100 years. The observation that peripheral immune functions can be modified by associative learning processes was first reported and investigated… read more here.
Keywords: immunological neuroendocrine; pavlovian conditioning; neuroendocrine functions; peripheral immune ... See more keywords
Intravenous Cellular Therapies for Acute Ischemic Stroke
Sign Up to like & getrecommendations! Published in 2018 at "Stroke"
DOI: 10.1161/strokeaha.118.018287
Abstract: The promise of cellular therapies as a treatment for stroke and other injuries and diseases of the central nervous system (CNS) has compelled researchers, clinicians, patients, and the public for the last 2 decades. Various… read more here.
Keywords: ischemic stroke; tissue; peripheral immune; cellular therapies ... See more keywords
Leukemia inhibitory factor modulates the peripheral immune response in a rat model of emergent large vessel occlusion
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-018-1326-y
Abstract: BackgroundThe migration of peripheral immune cells and splenocytes to the ischemic brain is one of the major causes of delayed neuroinflammation after permanent large vessel stroke. Other groups have demonstrated that leukemia inhibitory factor (LIF),… read more here.
Keywords: treatment; interferon; peripheral immune; interferon gamma ... See more keywords
Reversibility of the effects of natalizumab on peripheral immune cell dynamics in MS patients
Sign Up to like & getrecommendations! Published in 2017 at "Neurology"
DOI: 10.1212/wnl.0000000000004485
Abstract: Objective: To characterize the reversibility of natalizumab-mediated changes in pharmacokinetics/pharmacodynamics in patients with multiple sclerosis (MS) following therapy interruption. Methods: Pharmacokinetic/pharmacodynamic data were collected in the Safety and Efficacy of Natalizumab in the Treatment of… read more here.
Keywords: reversibility; immune cell; treatment; peripheral immune ... See more keywords
Lymphocyte deficiency alters the transcriptomes of oligodendrocytes, but not astrocytes or microglia
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0279736
Abstract: Though the brain was long characterized as an immune-privileged organ, findings in recent years have shown extensive communications between the brain and peripheral immune cells. We now know that alterations in the peripheral immune system… read more here.
Keywords: peripheral immune; brain; alters transcriptomes; glial cells ... See more keywords
The Peripheral Immune Landscape in a Patient with Myocarditis after the Administration of BNT162b2 mRNA Vaccine
Sign Up to like & getrecommendations! Published in 2022 at "Molecules and Cells"
DOI: 10.14348/molcells.2022.0031
Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has posed a serious threat to global public health. A novel vaccine made from messenger RNA (mRNA) has been developed and approved for use at an… read more here.
Keywords: myocarditis; landscape patient; peripheral immune; bnt162b2 ... See more keywords
The peripheral immune status of granulocytic myeloid-derived suppressor cells correlates the survival in advanced gastric cancer patients receiving cisplatin-based chemotherapy
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.18297
Abstract: Background The prognostic significance of peripheral immune status in patients with advanced gastric cancer (AGC) remains unclear. Results From July 2013 through December 2014, 37 patients were enrolled. Among patients with 25 subsets of immune… read more here.
Keywords: advanced gastric; peripheral immune; cisplatin; immune status ... See more keywords