T cells dominate peripheral inflammation in a cross‐sectional analysis of obesity‐associated diabetes
Sign Up to like & getrecommendations! Published in 2022 at "Obesity"
DOI: 10.1002/oby.23528
Abstract: Myeloid cells dominate metabolic disease‐associated inflammation (metaflammation) in mouse obesity, but the contributions of myeloid cells to the peripheral inflammation that fuels sequelae of human obesity are untested. This study used unbiased approaches to rank… read more here.
Keywords: inflammation; peripheral inflammation; myeloid cells; dominate peripheral ... See more keywords
Chronic low-grade peripheral inflammation is associated with ultra resistant schizophrenia. Results from the FACE-SZ cohort
Sign Up to like & getrecommendations! Published in 2018 at "European Archives of Psychiatry and Clinical Neuroscience"
DOI: 10.1007/s00406-018-0908-0
Abstract: A high rate of patients with schizophrenia (SZ) does not sufficiently respond to antipsychotic medication, which is associated with relapses and poor outcomes. Chronic peripheral inflammation has been repeatedly associated with schizophrenia risk and particularly… read more here.
Keywords: schizophrenia; inflammation associated; inflammation; peripheral inflammation ... See more keywords
Evidence of fatigue, disordered sleep and peripheral inflammation, but not increased brain TSPO expression, in seasonal allergy: A [11C]PBR28 PET study
Sign Up to like & getrecommendations! Published in 2018 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.10.013
Abstract: Allergy is associated with non-specific symptoms such as fatigue, sleep problems and impaired cognition. One explanation could be that the allergic inflammatory state includes activation of immune cells in the brain, but this hypothesis has… read more here.
Keywords: tspo; fatigue; peripheral inflammation; allergy ... See more keywords
Chronic Peripheral Inflammation Causes a Region-Specific Myeloid Response in the Central Nervous System.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.02.109
Abstract: Systemic immune dysregulation contributes to the development of neuropsychiatric and neurodegenerative diseases. The precise effect of chronic peripheral immune stimulation on myeloid cells across anatomical brain regions is unclear. Here, we demonstrate brain-region-specific differences in… read more here.
Keywords: myeloid; chronic peripheral; peripheral inflammation; region specific ... See more keywords
Effects of Peripheral Immune Challenge on In Vivo Firing of Basolateral Amygdala Neurons in Adult Male Rats
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.08.017
Abstract: Peripheral inflammation often causes changes in mood and emergence of depressive behavior, and is characterized by a group of physical manifestations including lethargy, malaise, listlessness, decreased appetite, anhedonia, and fever. These behavioral changes are induced… read more here.
Keywords: inflammation; peripheral inflammation; bla; basolateral amygdala ... See more keywords
Redefining peripheral inflammation signature in schizophrenia based on the real-world FACE-SZ cohort
Sign Up to like & getrecommendations! Published in 2021 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2021.110335
Abstract: BACKGROUND Peripheral inflammation is associated with impaired prognosis in schizophrenia (SZ). Highly sensitive C-reactive protein (hs-CRP) is the most used inflammatory biomarker in daily practice. However, no consensual cut-off has been determined to date to… read more here.
Keywords: face cohort; schizophrenia; inflammation; peripheral inflammation ... See more keywords
Visceral fat-related systemic inflammation and the adolescent brain: a mediating role of circulating glycerophosphocholines
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Obesity"
DOI: 10.1038/s41366-018-0202-2
Abstract: ObjectiveLife-long maintenance of brain health is important for the prevention of cognitive impairment in older age. Low-grade peripheral inflammation associated with excess visceral fat (VF) may influence brain structure and function. Here we examined (i)… read more here.
Keywords: inflammation; peripheral inflammation; processing speed; brain ... See more keywords
The Effects of Peripheral Inflammation on the Brain—A Neuroimaging Perspective
Sign Up to like & getrecommendations! Published in 2022 at "Harvard Review of Psychiatry"
DOI: 10.1097/hrp.0000000000000323
Abstract: Abstract In the field of neuropsychiatry, neuroinflammation is one of the prevailing hypotheses to explain the pathophysiology of mood and psychotic disorders. Neuroinflammation encompasses an ill-defined set of pathophysiological processes in the central nervous system… read more here.
Keywords: neuroimaging studies; peripheral inflammation; effects peripheral; brain neuroimaging ... See more keywords
Peripheral inflammation affects modulation of nociceptive synaptic transmission in the spinal cord induced by N‐arachidonoylphosphatidylethanolamine
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Pharmacology"
DOI: 10.1111/bph.13849
Abstract: Endocannabinoids play an important role in modulating spinal nociceptive signalling, crucial for the development of pain. The cannabinoid CB1 receptor and the TRPV1 cation channel are both activated by the endocannabinoid anandamide, a product of… read more here.
Keywords: transmission; affects modulation; inflammation affects; peripheral inflammation ... See more keywords
Peripheral inflammation exacerbates α‐synuclein toxicity and neuropathology in Parkinson's models
Sign Up to like & getrecommendations! Published in 2020 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12644
Abstract: Parkinson’s disease and related disorders are devastating neurodegenerative pathologies. Since α‐synuclein was identified as a main component of Lewy bodies and neurites, efforts have been made to clarify the pathogenic mechanisms of α‐synuclein's detrimental effects.… read more here.
Keywords: inflammation exacerbates; neuropathology; parkinson; inflammation ... See more keywords
Central and Peripheral Inflammation: Connecting the Immune Responses of Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Parkinson's Disease"
DOI: 10.3233/jpd-223241
Abstract: Inflammation has increasingly become a focus of study in regards to Parkinson’s disease (PD). Moreover, both central and peripheral sources of inflammation have been implicated in the pathogenesis of PD. Central inflammation consisting of activated… read more here.
Keywords: inflammation; peripheral inflammation; central peripheral; parkinson disease ... See more keywords