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Published in 2021 at "PharmaNutrition"
DOI: 10.1016/j.phanu.2021.100278
Abstract: Abstract Background A poor-quality diet may contribute to chronic levels of inflammation and alter susceptibility to pain via activation of immune cells. Methods Here we examined the effect of a human-relevant Standard American Diet (SAD)… read more here.
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Published in 2021 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2020.110136
Abstract: BACKGROUND Mood disorders (major depressive disorder, MDD, and bipolar disorder, BD) are considered leading causes of life-long disability worldwide, where high rates of no response to treatment or relapse and delays in receiving a proper… read more here.
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Published in 2021 at "Acta neuropsychiatrica"
DOI: 10.1017/neu.2021.39
Abstract: BACKGROUND Neuroinflammation and brain structural abnormalities are found in bipolar disorder (BD). Elevated levels of cytokines and chemokines have been detected in the serum and cerebrospinal fluid of patients with BD. This study investigated the… read more here.
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Published in 2017 at "Molecular Pain"
DOI: 10.1177/1744806917715210
Abstract: A diverse array of G protein-coupled receptors (GPCRs) is implicated in the modulation of nociception. The efficacy and potency of several GPCR agonists change as a consequence of peripheral inflammatory injury. Whether these changes reflect… read more here.
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Published in 2025 at "BMC Neurology"
DOI: 10.1186/s12883-025-04128-1
Abstract: Entacapone has been widely used in the treatment of moderate to advanced Parkinson’s disease (PD), and its efficacy for motor symptoms has been well-known from several clinical trials and long-term clinical use. The efficacy of… read more here.
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Published in 2020 at "BMC Cancer"
DOI: 10.1186/s12885-020-07105-8
Abstract: Background Hepatocellular carcinoma (HCC) is an inflammation-related cancer, where nonresolving inflammation contributes to its development and progression. Peripheral inflammatory cells have been shown to be associated with the prognosis of various types of cancer. The… read more here.
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Published in 2024 at "European Psychiatry"
DOI: 10.1192/j.eurpsy.2024.1651
Abstract: Introduction Suicide is the most severe consequence of major depressive disorder (MDD). The most novel researches assume the role of immunological dysregulation in the background – several studies have reported alterations of inflammatory cells related… read more here.
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Published in 2024 at "Journal of integrative neuroscience"
DOI: 10.31083/j.jin2303064
Abstract: BACKGROUND Pannexin1 (Panx1) is a membrane channel expressed in different cells of the nervous system and is involved in several pathological conditions, including pain and inflammation. At the central nervous system, the role of Panx1… read more here.
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Published in 2025 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2025.1474812
Abstract: Objective This pilot study aims to investigate the association between peripheral inflammatory cytokines and motor and non-motor symptoms in patients with both Parkinson’s disease (PD) and type 2 diabetes mellitus (T2DM) and the underlying mechanisms.… read more here.
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Published in 2025 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2025.1598911
Abstract: Objective The purpose of this study was to explore brain metabolic correlates of peripheral inflammatory markers in patients with cervical cancer (CC). Methods Cervical cancer (CC) patients (267) without treatments who underwent [18F] Fluorodeoxyglucose ([18F]FDG)… read more here.
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Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.00473
Abstract: Peripheral inflammatory hyperalgesia depends on the sensitization of primary nociceptive neurons. Inflammation drives molecular alterations not only locally but also in the dorsal root ganglion (DRG) where interleukin-1 beta (IL-1β) and purinoceptors are upregulated. Activation… read more here.