Peripheral Innate Immune Activation Correlates With Disease Severity in GRN Haploinsufficiency
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DOI: 10.3389/fneur.2019.01004
Abstract: Objective: To investigate associations between peripheral innate immune activation and frontotemporal lobar degeneration (FTLD) in progranulin gene (GRN) haploinsufficiency. Methods: In this cross-sectional study, ELISA was used to measure six markers of innate immunity (sCD163,… read more here.
Keywords: peripheral innate; immune activation; grn; grn haploinsufficiency ... See more keywords