The efficacy and safety of botulinum toxin type A in treatment of trigeminal neuralgia and peripheral neuropathic pain: A meta‐analysis of randomized controlled trials
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DOI: 10.1002/brb3.1409
Abstract: Although recent studies have shown that botulinum toxin‐A (BTX‐A) has a good analgesic effect on trigeminal neuralgia (TN) and peripheral neuropathic pain (PNP), the quality of evidence is low due to limited data. This meta‐analysis… read more here.
Keywords: peripheral neuropathic; neuralgia peripheral; trigeminal neuralgia; neuropathic pain ... See more keywords
Capsaicin 8% Dermal Patch: A Review in Peripheral Neuropathic Pain
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DOI: 10.1007/s40265-018-0982-7
Abstract: The adhesive capsaicin dermal patch (Qutenza®) delivers a high concentration (8% w/w) of synthetic capsaicin, a highly selective agonist of transient receptor potential vanilloid-1 (TRPV-1), directly to the site of pain. The capsaicin 8% dermal… read more here.
Keywords: peripheral neuropathic; pain; dermal patch; capsaicin dermal ... See more keywords
Duloxetine ameliorates the impairment of diffuse noxious inhibitory control in rat models of peripheral neuropathic pain and knee osteoarthritis pain
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DOI: 10.1016/j.neulet.2020.134990
Abstract: Diffuse noxious inhibitory control (DNIC) is a phenomenon to reflect descending pain modulation in animals. Conditioned pain modulation (CPM) is the human counterpart of DNIC and is reduced in patients with several chronic pain conditions.… read more here.
Keywords: pwt; peripheral neuropathic; duloxetine; neuropathic pain ... See more keywords
Microglia-independent peripheral neuropathic pain in male and female mice
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DOI: 10.1097/j.pain.0000000000002643
Abstract: Supplemental Digital Content is Available in the Text. It is believed that peripheral neuropathic pain is dependent on activation of microglia in the spinal cord, but human trials targeting these cells have been disappointing. We… read more here.
Keywords: female mice; peripheral neuropathic; microglia independent; male female ... See more keywords
Analgesic effect of perineural local anesthetics, steroids, and conventional medical management for trauma and compression-related peripheral neuropathic pain: a retrospective cohort study
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DOI: 10.1097/pr9.0000000000000945
Abstract: Supplemental Digital Content is Available in the Text. Perineural local anesthetic and steroid injections do not confer an analgesic benefit for trauma- or compression-related peripheral neuropathic pain. A higher degree of catastrophizing reduces the analgesic… read more here.
Keywords: perineural local; trauma compression; peripheral neuropathic; compression related ... See more keywords
Peripheral Neuropathic Pain Following Breast Cancer: Effectiveness and Tolerability of High-Concentration Capsaicin Patch
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DOI: 10.2147/jpr.s341378
Abstract: Purpose Data supporting the use of high-concentration capsaicin patches (HCCPs) in breast cancer (BC) patients and BC survivors (BCSs) with peripheral neuropathic pain (PNP) are limited. This observational study evaluated the effectiveness and safety of… read more here.
Keywords: peripheral neuropathic; breast cancer; high concentration; pain ... See more keywords
Mechanisms Underlying Gastrodin Alleviating Vincristine-Induced Peripheral Neuropathic Pain
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DOI: 10.3389/fphar.2021.744663
Abstract: Gastrodin (GAS) is the main bioactive ingredient of Gastrodia, a famous Chinese herbal medicine widely used as an analgesic, but the underlying analgesic mechanism is still unclear. In this study, we first observed the effects… read more here.
Keywords: vincristine induced; induced peripheral; neuropathic pain; gas ... See more keywords
Implantable Peripheral Nerve Stimulation for Peripheral Neuropathic Pain: A Systematic Review of Prospective Studies
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DOI: 10.3390/biomedicines10102606
Abstract: Peripheral nerve stimulation (PNS) has been utilized for over 50 years with accumulating evidence of efficacy in a variety of chronic pain conditions. The level and strength of evidence supporting the use of PNS for… read more here.
Keywords: peripheral nerve; peripheral neuropathic; prospective studies; nerve stimulation ... See more keywords
Topical Treatments and Their Molecular/Cellular Mechanisms in Patients with Peripheral Neuropathic Pain—Narrative Review
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DOI: 10.3390/pharmaceutics13040450
Abstract: Neuropathic pain in humans results from an injury or disease of the somatosensory nervous system at the peripheral or central level. Despite the considerable progress in pain management methods made to date, peripheral neuropathic pain… read more here.
Keywords: molecular cellular; peripheral neuropathic; topical treatments; neuropathic pain ... See more keywords
8% Capsaicin Patch in Treatment of Peripheral Neuropathic Pain.
Sign Up to like & getrecommendations! Published in 2020 at "Pain physician"
DOI: 10.36076/ppj.2020/23/e541
Abstract: BACKGROUND Neuropathic pain is a complex condition that is difficult to control and has a high impact on quality of life. 8% Capsaicin patch can be a therapeutic strategy in the treatment of peripheral neuropathic… read more here.
Keywords: pain; treatment; capsaicin patch; peripheral neuropathic ... See more keywords