Ketamine potentiates TRPV1 receptor signaling in the peripheral nociceptive pathways.
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DOI: 10.1016/j.bcp.2020.114210
Abstract: TRPV1 is a cation channel expressed in peripheral nociceptive pathways and its activation can trigger nociception signals to the brain. Ketamine is an intravenous anesthetic routinely used for anesthesia induction and with potent analgesic activity.… read more here.
Keywords: nociceptive pathways; ketamine; peripheral nociceptive; trpv1 receptor ... See more keywords