Structural Features and Energetics of the Periplasmic Entrance Opening of the Outer Membrane Channel TolC Revealed by Molecular Dynamics Simulation and Markov State Model Analysis
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DOI: 10.1021/acs.jcim.8b00957
Abstract: TolC is a channel protein responsible for substrate translocation across the outer membrane, and it is also a part of the tripartite multidrug efflux pumps in Gram-negative bacteria. The crystal structure of TolC shows that… read more here.
Keywords: markov state; periplasmic entrance; outer membrane; tolc ... See more keywords