Articles with "periplocin" as a keyword



Periplocin Induces Apoptosis of Pancreatic Cancer Cells through Autophagy via the AMPK/mTOR Pathway

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Published in 2022 at "Journal of Oncology"

DOI: 10.1155/2022/8055004

Abstract: Periplocin, a natural compound, has been shown to induce apoptosis in a variety of cancer cells. However, no research has been conducted to demonstrate that Periplocin has a regulatory effect on autophagy. This study is… read more here.

Keywords: periplocin; pancreatic cancer; ampk mtor; mtor pathway ... See more keywords
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Cardiac Glycosides Induce Immunogenic Changes in Myeloma Cells and Enhance the Efficacy of Monoclonal and Bispecific Antibody Therapy

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Published in 2024 at "Blood"

DOI: 10.1182/blood-2024-200981

Abstract: Background: Cardiac glycosides (CGs) are naturally-occurring compounds with a characteristic sugar structure that enhance myocardial contractility by inhibiting Na/K ATPase in cardiomyocytes. Several CGs, such as digoxin and digitoxin, can be used to treat heart… read more here.

Keywords: periplocin; therapy; antibody; cell ... See more keywords