The effect of strontium ranelate on titanium particle-induced periprosthetic osteolysis regulated by WNT/β-catenin signaling in vivo and in vitro
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DOI: 10.1042/bsr20203003
Abstract: Abstract Aseptic loosening following periprosthetic osteolysis is the primary complication that limits the lifetime of total joint arthroplasty (TJA). The wear particles trigger a chronic inflammation response in the periprosthetic tissue and turn over the… read more here.
Keywords: periprosthetic osteolysis; strontium ranelate; ranelate; particle induced ... See more keywords
Catastrophic Periprosthetic Osteolysis in Total Hip Arthroplasty at 20 Years: A Case Report and Literature Review
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DOI: 10.1111/os.13322
Abstract: Periprosthetic osteolysis is a serious complication following total hip arthroplasty (THA). However, most orthopedic surgeons only focus on bone loss and hip reconstruction. Thus, it was required to understand the treatment algorithm for periprosthetic osteolysis… read more here.
Keywords: osteolysis; total hip; catastrophic periprosthetic; periprosthetic osteolysis ... See more keywords
Cimifugin Suppresses NF-κB Signaling to Prevent Osteoclastogenesis and Periprosthetic Osteolysis
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DOI: 10.3389/fphar.2021.724256
Abstract: Background: Aseptic loosening of prosthesis (ALP) is one of the most common long-term complications of knee and hip arthroplasty. Wear particle-induced osteoclastogenesis and subsequent periprosthetic osteolysis account for the morbidity of ALP. Here, we investigate… read more here.
Keywords: periprosthetic osteolysis; cimifugin; cim; bone ... See more keywords
Pyroptosis in Periprosthetic Osteolysis
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DOI: 10.3390/biom12121733
Abstract: Periprosthetic osteolysis (PPO) along with aseptic loosening (AL) caused by wear particles after artificial joint replacement is the key factor in surgical failure and subsequent revision surgery, however, the precise molecular mechanism underlying PPO remains… read more here.
Keywords: periprosthetic osteolysis; pyroptosis; ppo; pyroptosis periprosthetic ... See more keywords