Synopsis of a clinical practice guideline for pancreatic ductal adenocarcinoma with peritoneal dissemination in Japan; Japan Peritoneal Malignancy Study Group.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of hepato-biliary-pancreatic sciences"
DOI: 10.1002/jhbp.1085
Abstract: BACKGROUND/PURPOSE Patients with pancreatic ductal adenocarcinoma (PDAC) with peritoneal dissemination have a dismal prognosis because discontinuation of systemic chemotherapy is required for massive ascites or poor performance status. The natural history, diagnosis and treatment of… read more here.
Keywords: japan; pdac peritoneal; dissemination; guideline ... See more keywords
Intraperitoneal cancer-immune microenvironment promotes peritoneal dissemination of gastric cancer
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DOI: 10.1080/2162402x.2019.1671760
Abstract: ABSTRACT A solid tumor consists of cancer and stromal cells, which comprise the tumor microenvironment (TME). Tumor-associated macrophages (TAMs) are usually abundant in the TME, contributing to tumor progression. In cases of peritoneal dissemination of… read more here.
Keywords: peritoneal dissemination; cancer; gastric cancer; tumor ... See more keywords
Intraperitoneal administration of nanoparticles containing tocopheryl succinate prevents peritoneal dissemination
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DOI: 10.1111/cas.15321
Abstract: Intraperitoneal administration of anticancer nanoparticles is a rational strategy for preventing peritoneal dissemination of colon cancer due to the prolonged retention of nanoparticles in the abdominal cavity. However, instability of nanoparticles in body fluids causes… read more here.
Keywords: peritoneal dissemination; intraperitoneal administration; tocopheryl succinate; administration ... See more keywords
Abstract 1547:LOXL1is a novel responsible gene for peritoneal dissemination potentially via promoting EMT and motility in gastric cancer
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DOI: 10.1158/1538-7445.am2020-1547
Abstract: Background. In gastric cancer (GC), peritoneal dissemination (PD) occurs frequently and is incurable. We have identified 25 PD-associated genes in GC by in silico analysis in previous research. In this study, we focused on Lysyl… read more here.
Keywords: gastric cancer; loxl1 expression; expression; gene ... See more keywords
Molecular Determinants of Peritoneal Dissemination in Gastric Adenocarcinoma
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DOI: 10.1159/000526333
Abstract: Background: Peritoneal dissemination represents a poor prognostic indicator in gastric cancer. Despite a comprehensive molecular characterization of this disease, no peritoneal dissemination-specific signature has been identified, limiting the tailoring of the surgical and oncological treatments.… read more here.
Keywords: gastric adenocarcinoma; molecular determinants; peritoneal dissemination; dissemination ... See more keywords
α2,3-sialyltransferase type I regulates migration and peritoneal dissemination of ovarian cancer cells
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DOI: 10.18632/oncotarget.15994
Abstract: Epithelial ovarian cancer (EOC) has the highest mortality rate among gynecologic cancers due to advanced stage presentation, peritoneal dissemination, and refractory ascites at diagnosis. We investigated the role of α2,3-sialyltransferase type I (ST3GalI) by analyzing… read more here.
Keywords: st3gali; migration; ovarian cancer; cancer ... See more keywords
Treating an Intractable Jejunocutaneous Fistula by Endoscopic Metallic Stent Placement: A Case Report of Successful Palliative Endoscopic Treatment in a Case Demonstrating Peritoneal Dissemination with Terminal Stage Gastric Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Internal Medicine"
DOI: 10.2169/internalmedicine.9331-22
Abstract: A 74-year-old woman with recurrent gastric cancer underwent laparotomy for peritoneal dissemination, and the damaged jejunum formed a jejunocutaneous fistula. Because conservative treatment alone could not cure the fistula, we performed an endoscopic placement of… read more here.
Keywords: jejunocutaneous fistula; placement; peritoneal dissemination; case ... See more keywords
Successful Treatment of Intrahepatic Cholangiocarcinoma With Liver/Lung Metastasis and Peritoneal Dissemination After Liver Resection
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DOI: 10.21873/anticanres.15811
Abstract: Background/Aim: Intrahepatic cholangiocarcinoma (ICC) is increasing in incidence and has a poor prognosis. Case Report: A 79-year-old woman with two liver tumors was referred to our institution. The tumors demonstrated irregular margins and continuous peripheral… read more here.
Keywords: metastasis; liver; intrahepatic cholangiocarcinoma; lung ... See more keywords
Construction of a Nomogram Model for Predicting Peritoneal Dissemination in Gastric Cancer Based on Clinicopathologic Features and Preoperative Serum Tumor Markers
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DOI: 10.3389/fonc.2022.844786
Abstract: Background Peritoneal dissemination (PD) is the most common mode of metastasis for advanced gastric cancer (GC) with poor prognosis. It is of great significance to accurately predict preoperative PD and develop optimal treatment strategies for… read more here.
Keywords: peritoneal dissemination; gastric cancer; model; tumor ... See more keywords
Predicting Peritoneal Dissemination of Gastric Cancer in the Era of Precision Medicine: Molecular Characterization and Biomarkers
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DOI: 10.3390/cancers12082236
Abstract: Gastric cancer (GC) is a leading cause of worldwide cancer-related death. Being a highly heterogeneous disease, the current treatment of GC has been suboptimal due to the lack of subtype-dependent therapies. Peritoneal dissemination (PD) is… read more here.
Keywords: medicine; gastric cancer; diffuse type; cancer ... See more keywords
Intraperitoneal Paclitaxel Treatment for Patients with Pancreatic Ductal Adenocarcinoma with Peritoneal Dissemination Provides a Survival Benefit
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DOI: 10.3390/cancers14051354
Abstract: Simple Summary Pancreatic ductal adenocarcinoma (PDAC) with peritoneal dissemination is a highly lethal disease. Recently, promising activity of intraperitoneal chemotherapy with paclitaxel (i.p.-PTX) has been observed in patients with peritoneal dissemination. We conducted a retrospective… read more here.
Keywords: ptx group; group; treatment; peritoneal dissemination ... See more keywords