P1140THE REDUCTION OF THE SIEVING OF SODIUM IS THE FIRST AND EARLY FUNCTIONAL CHANGE OF PERITONEAL MEMBRANE IN A LARGE PATIENT POPULATION ON PERITONEAL DIALYSIS
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DOI: 10.1093/ndt/gfaa142.p1140
Abstract: The reduction whit time of peritoneal removal of salt and water is an important cause of reduced patient and technique survival in peritoneal (PD) patients. Solute transport increase after the start of PD and continue… read more here.
Keywords: reduction; peritoneal membrane; test; membrane ... See more keywords
#3214 The thiolomic profile of peritoneal membrane fibrosis: a hypothesis-driven research
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DOI: 10.1093/ndt/gfaf116.0715
Abstract: Our research group is actively searching for novel pharmacological strategies to protect the peritoneal membrane from fibrosis, a major challenge in maintaining the long-term effectiveness of peritoneal dialysis (PD) [1, 2]. While some protective agents… read more here.
Keywords: fibrosis; thiol; membrane fibrosis; profile ... See more keywords
#626 Association between peritoneal uric acid clearance, inflammation, and peritoneal membrane function in normouricemic patients undergoing peritoneal dialysis
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DOI: 10.1093/ndt/gfaf116.1576
Abstract: Elevated uric acid (UA), a byproduct of purine metabolism, is known to contribute to oxidative stress and inflammation. In patients undergoing peritoneal dialysis (PD), efficient clearance of UA is crucial for regulating systemic UA levels.… read more here.
Keywords: membrane function; peritoneal membrane; clearance; inflammation ... See more keywords
Matrix metalloproteinase 9 is associated with peritoneal membrane solute transport and induces angiogenesis through &bgr;-catenin signaling
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DOI: 10.1093/ndt/gfw076
Abstract: Background. For patients using peritoneal dialysis (PD), the peritoneal membrane can develop fibrosis and angiogenesis, leading to ultrafiltration failure, chronic hypervolemia and increased risk of technique failure and mortality. Matrix metalloproteinases (MMPs), and specifically the… read more here.
Keywords: peritoneal membrane; bgr catenin; mmp9;
Alpha‐klotho and peritoneal membrane status: A hypothesis generating study
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DOI: 10.1111/eci.13903
Abstract: Long‐term success of peritoneal dialysis relies on the integrity of the peritoneal membrane. This proof‐of‐concept study addressed the hypothesis that fibrosis is already present in the membrane at pre‐dialysis and that the membrane status is… read more here.
Keywords: hypothesis; peritoneal membrane; membrane; membrane status ... See more keywords
Dissolved molecular hydrogen (H2) in Peritoneal Dialysis (PD) solutions preserves mesothelial cells and peritoneal membrane integrity
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DOI: 10.1186/s12882-017-0741-0
Abstract: BackgroundPeritoneal dialysis (PD) is used as renal replacement therapy in patients with end-stage kidney disease. However, peritoneal membrane failure remains problematic and constitutes a critical cause of PD discontinuation. Recent studies have revealed the unique… read more here.
Keywords: molecular hydrogen; cells peritoneal; group; membrane integrity ... See more keywords
Dapagliflozin in peritoneal dialysis patients: a pilot study evaluating peritoneal membrane function
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DOI: 10.1186/s12882-023-03429-2
Abstract: Patients taking SGLT-2 inhibitors may experience delayed peritoneal fibrosis, better ultrafiltration of water and toxins, and higher survival rates. We aimed to evaluate the possible effects of Dapagliflozin in changing the peritoneal solute transfer rate,… read more here.
Keywords: dialysis patients; peritoneal membrane; dialysis; peritoneal dialysis ... See more keywords
Mechanisms of Peritoneal Fibrosis: Focus on Immune Cells–Peritoneal Stroma Interactions
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DOI: 10.3389/fimmu.2021.607204
Abstract: Peritoneal fibrosis is characterized by abnormal production of extracellular matrix proteins leading to progressive thickening of the submesothelial compact zone of the peritoneal membrane. This process may be caused by a number of insults including… read more here.
Keywords: peritoneal fibrosis; peritoneal membrane; cells peritoneal; fibrosis ... See more keywords
Fibrosis of Peritoneal Membrane, Molecular Indicators of Aging and Frailty Unveil Vulnerable Patients in Long-Term Peritoneal Dialysis
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DOI: 10.3390/ijms24055020
Abstract: Peritoneal membrane status, clinical data and aging-related molecules were investigated as predictors of long-term peritoneal dialysis (PD) outcomes. A 5-year prospective study was conducted with the following endpoints: (a) PD failure and time until PD… read more here.
Keywords: long term; peritoneal dialysis; mace; peritoneal membrane ... See more keywords
Impact of Metabolomics Technologies on the Assessment of Peritoneal Membrane Profiles in Peritoneal Dialysis Patients: A Systematic Review
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DOI: 10.3390/metabo12020145
Abstract: Peritoneal dialysis (PD) is an effective and frequent dialysis modality in adults, particularly preferred in infants and young children with end-stage renal disease (ESRD). Long-term exposure of the peritoneal membrane to dialysis solutions results in… read more here.
Keywords: peritoneal dialysis; impact metabolomics; dialysis; metabolomics technologies ... See more keywords