Articles with "peritoneal metastasis" as a keyword



Accurate and Rapid Detection of Peritoneal Metastasis from Gastric Cancer by AI-Assisted Stimulated Raman Molecular Cytology.

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Published in 2023 at "Advanced science"

DOI: 10.1002/advs.202300961

Abstract: Peritoneal metastasis (PM) is the mostcommon form of distant metastasis and one of the leading causes of death in gastriccancer (GC). For locally advanced GC, clinical guidelines recommend peritoneal lavage cytology for intraoperative PM detection.… read more here.

Keywords: peritoneal metastasis; raman molecular; detection; cytology ... See more keywords

Clinical outcomes of curative surgical resection of peritoneal metastasis in patients with colorectal cancer: A long‐term follow‐up study

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Published in 2022 at "Cancer Medicine"

DOI: 10.1002/cam4.5195

Abstract: Colorectal cancer with peritoneal metastasis (PM) has been considered a non‐curative disease. PM is associated with reduced overall survival (OS) and worse prognosis compared with metastasis at other sites. We aimed to investigate the treatment… read more here.

Keywords: metastasis; long term; peritoneal metastasis; colorectal cancer ... See more keywords

Study of SOX combined with intraperitoneal high‐dose paclitaxel in gastric cancer with synchronous peritoneal metastasis: A phase II single‐arm clinical trial

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Published in 2022 at "Cancer Medicine"

DOI: 10.1002/cam4.5277

Abstract: Intraperitoneal paclitaxel is proved to be efficient for peritoneal metastasis of gastric cancer. It remains uncertain the efficacy and safety of the triplets regimen which combined intraperitoneal high‐dose paclitaxel with systemic SOX in gastric cancer… read more here.

Keywords: peritoneal metastasis; gastric cancer; high dose; cancer ... See more keywords

Genomic landscape defines peritoneal metastatic pattern and related target of peritoneal metastasis in colorectal cancer

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Published in 2024 at "International Journal of Cancer"

DOI: 10.1002/ijc.35005

Abstract: The primary objective of this study is to develop a prediction model for peritoneal metastasis (PM) in colorectal cancer by integrating the genomic features of primary colorectal cancer, along with clinicopathological features. Concurrently, we aim… read more here.

Keywords: colorectal cancer; genomic landscape; cancer; peritoneal metastasis ... See more keywords

Oncological impact of intraperitoneal chemotherapy after cytoreductive surgery for patients with colorectal peritoneal metastasis: A bi‐institutional retrospective analysis

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Published in 2022 at "Journal of Surgical Oncology"

DOI: 10.1002/jso.27171

Abstract: There is a paucity of evidence on the value of intraperitoneal chemotherapy (IPC) following cytoreductive surgery (CRS) for colorectal peritoneal metastasis. This study aimed to evaluate the association between mitomycin C‐IPC and survival outcomes following… read more here.

Keywords: colorectal peritoneal; cytoreductive surgery; intraperitoneal chemotherapy; peritoneal metastasis ... See more keywords

Peritoneal metastasis of a brainstem anaplastic ganglioglioma in a 2-year-old boy: case report and literature review

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Published in 2022 at "Child's Nervous System"

DOI: 10.1007/s00381-022-05516-5

Abstract: Anaplastic gangliogliomas (AGG) are rare tumors of the central nervous system (CNS) that commonly affect children and young adults, with an unusual infratentorial presentation, which is related to hydrocephalus and a worse prognosis. We report… read more here.

Keywords: brainstem; year old; case; report ... See more keywords
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Oxaliplatin versus mitomycin C in HIPEC for peritoneal metastasis from colorectal cancer: a systematic review and meta-analysis of comparative studies

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Published in 2020 at "International Journal of Colorectal Disease"

DOI: 10.1007/s00384-020-03702-y

Abstract: Hyperthermic intraperitoneal perfusion chemotherapy (HIPEC) following cytoreductive surgery (CRS) has been applied for peritoneal metastasis (PM) from colorectal cancer (CRC). This study aimed to compare oxaliplatin (OX) with mitomycin C (MMC) in HIPEC for PM… read more here.

Keywords: metastasis colorectal; colorectal cancer; peritoneal metastasis; hipec ... See more keywords

Neoantigen mRNA vaccines induce progenitor-exhausted T cells that support anti-PD-1 therapy in gastric cancer with peritoneal metastasis

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Published in 2025 at "Gastric Cancer"

DOI: 10.1007/s10120-025-01640-8

Abstract: Gastric cancer with peritoneal metastasis is associated with a poor prognosis. Current treatments, including the first-line therapy of combination chemotherapy with nivolumab for advanced recurrent gastric cancer, have shown limited efficacy against peritoneal dissemination. In… read more here.

Keywords: cancer; mrna; therapy; gastric cancer ... See more keywords

SMOC2 promotes peritoneal metastasis of gastric cancer involving Wnt/β-catenin pathway modulation and inducing angiogenesis

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Published in 2025 at "Clinical and Experimental Medicine"

DOI: 10.1007/s10238-025-01914-6

Abstract: Gastric cancer (GC) is a leading cause of cancer-related deaths worldwide, with peritoneal metastasis commonly seen in advanced cases. Based on RNA-sequencing data from GEO dataset, we focused on the role of SMOC2, SPARC-related modular… read more here.

Keywords: involving wnt; smoc2 promotes; peritoneal metastasis; wnt catenin ... See more keywords

A Nitroreductase-Activated Chemiluminescent Prodrug for Real-Time Monitoring of Camptothecin Release in Peritoneal Metastasis Theranostics.

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Published in 2025 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.5c01674

Abstract: While most theranostic prodrugs utilize fluorescence for reporting, chemiluminescence offers superior signal-to-noise ratios. However, chemiluminescence-based prodrug systems remain relatively scarce. Herein, we report the development of CPT-NBz-CL, a novel hypoxia-responsive theranostic prodrug activated by nitroreductase… read more here.

Keywords: cpt nbz; chemiluminescence; peritoneal metastasis; camptothecin ... See more keywords

Nanomechanical Analysis of Living Small Extracellular Vesicles to Identify Gastric Cancer Cell Malignancy Based on a Biomimetic Peritoneum

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Published in 2024 at "ACS Nano"

DOI: 10.1021/acsnano.3c02285

Abstract: Gastric cancer is one of the most prevalent digestive malignancies. The lack of effective in vitro peritoneal models has hindered the exploration of the potential mechanisms behind gastric cancer’s peritoneal metastasis. An accumulating body of… read more here.

Keywords: cancer; nanomechanical analysis; peritoneum; gastric cancer ... See more keywords