Neutrophil Membrane‐Engineered Extracellular Vesicles from Perivascular Adipose Tissue‐Derived Stromal Cells for Atherosclerotic Lesion Resolution and Enhanced Vascular Graft Remodeling
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DOI: 10.1002/adfm.202503873
Abstract: Atherosclerosis is characterized by endothelial dysfunction and progressive plaque formation. Despite advancements in lipid‐lowering and anti‐inflammatory therapies, the repair of vascular damage and targeted delivery to atherosclerotic lesions remain critical challenges. Here, the development of… read more here.
Keywords: extracellular vesicles; neutrophil membrane; membrane engineered; engineered extracellular ... See more keywords
Expression of Melatonin Receptor 1 in Rat Mesenteric Artery and Perivascular Adipose Tissue and Vasoactive Action of Melatonin
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DOI: 10.1007/s10571-020-00928-w
Abstract: Melatonin is released by the pineal gland and can modulate cardiovascular system function via the G protein-coupled melatonin receptors MT 1 and MT 2 . Most vessels are surrounded by perivascular adipose tissue (PVAT), which… read more here.
Keywords: perivascular adipose; mesenteric artery; adipose tissue; melatonin ... See more keywords
Hesperidin reverses perivascular adipose-mediated aortic stiffness with aging
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DOI: 10.1016/j.exger.2017.08.003
Abstract: ABSTRACT We tested the hypothesis that hesperidin would reverse age‐related aortic stiffness, perivascular adipose (PVAT) mediated‐arterial stiffening and PVAT advanced glycation end‐products (AGE) accumulation. Aortic pulse wave velocity (aPWV) and intrinsic mechanical stiffness, two measures… read more here.
Keywords: mechanical stiffness; stiffness; age; perivascular adipose ... See more keywords
Reply: New Aspects of Vasospastic Angina: Coronary Adventitial and Perivascular Adipose Tissue Inflammation.
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DOI: 10.1016/j.jacc.2018.03.510
Abstract: We greatly appreciate Dr. Ciliberti and colleagues and Drs. Antonopoulos and Antoniades for their interests and comments on our recent study “Coronary adventitial and perivascular adipose tissue inflammation in patients with vasospastic angina” [(1)][1]. First,… read more here.
Keywords: coronary adventitial; perivascular adipose; adipose tissue; adventitial perivascular ... See more keywords
Inflammatory cells, ceramides, and expression of proteases in perivascular adipose tissue adjacent to human abdominal aortic aneurysms
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DOI: 10.1016/j.jvs.2015.12.056
Abstract: Background: Abdominal aortic aneurysm (AAA) is a deadly irreversible weakening and distension of the abdominal aortic wall. The pathogenesis of AAA remains poorly understood. Investigation into the physical and molecular characteristics of perivascular adipose tissue… read more here.
Keywords: perivascular adipose; tissue adjacent; adipose tissue; abdominal aortic ... See more keywords
Long-Term In Vivo Administration of Panaxynol Alleviates Diabetes-Induced Vascular Calcification by Modulating Sirt6-Mediated sEH Function in Perivascular Adipose Tissue
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DOI: 10.1021/acs.jafc.5c01982
Abstract: Panaxynol (PA), a bioactive compound found in carrots and other Apiaceae plants, holds promise for managing diabetes-related vascular complications. This study investigated the long-term effects of PA on diabetes-induced vascular calcification (DVC) in db/db mice… read more here.
Keywords: diabetes induced; long term; vascular calcification; induced vascular ... See more keywords
Computer tomography-based assessment of perivascular adipose tissue in patients with abdominal aortic aneurysms
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DOI: 10.1038/s41598-024-71283-9
Abstract: This retrospective study investigates perivascular adipose tissue (PVAT) alterations in CT as a marker of inflammation in patients with abdominal aortic aneurysms (AAA). 100 abdominal CT scans of patients with abdominal aortic aneurysms and 100… read more here.
Keywords: patients abdominal; abdominal aortic; aortic aneurysms; perivascular adipose ... See more keywords
Endothelin-1 downregulates nuclear factor erythroid 2-related factor-2 and contributes to perivascular adipose tissue dysfunction in obesity.
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DOI: 10.1042/cs20240624
Abstract: Perivascular adipose tissue (PVAT) negatively regulates vascular muscle contraction. However, in the context of obesity, the PVAT releases vasoconstrictor substances that detrimentally affect vascular function. A pivotal player in this scenario is the peptide endothelin-1… read more here.
Keywords: pvat; obesity; dysfunction; factor ... See more keywords
Combined aerobic and resistance exercise training restores perivascular adipose tissue function in the thoracic aorta of rats with heart failure.
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DOI: 10.1042/cs20256965
Abstract: Exercise training (ET) is increasingly recognized as a beneficial non-pharmacological intervention for cardiovascular diseases. Our previous results demonstrated that the thoracic perivascular adipose tissue (tPVAT) of heart failure (HF) rats underwent a phenotypic shift from… read more here.
Keywords: exercise training; perivascular adipose; adipose tissue; exercise ... See more keywords
Perivascular adipocyte size is related to the lipid profile and inflammatory changes in a healthy population
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DOI: 10.1080/21623945.2025.2499500
Abstract: ABSTRACT Inflammatory changes in perivascular adipose tissue are associated with atherosclerotic lesions in the adjacent artery and can also be used as a marker in patient workup. While adipocyte size is known to be closely… read more here.
Keywords: inflammatory changes; adipocyte size; size; perivascular adipose ... See more keywords
Browning of Abdominal Aorta Perivascular Adipose Tissue Inhibits Adipose Tissue Inflammation.
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DOI: 10.1089/met.2017.0074
Abstract: Abstract Background: Perivascular adipose tissue (PVAT) can regulate vascular homeostasis by secreting various adipokines. This study investigated the effects of PVAT browning on its endocrine function. Methods: In the first section of our study, male… read more here.
Keywords: cold exposure; browning abdominal; perivascular adipose; tissue ... See more keywords