Expression of Melatonin Receptor 1 in Rat Mesenteric Artery and Perivascular Adipose Tissue and Vasoactive Action of Melatonin
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-020-00928-w
Abstract: Melatonin is released by the pineal gland and can modulate cardiovascular system function via the G protein-coupled melatonin receptors MT 1 and MT 2 . Most vessels are surrounded by perivascular adipose tissue (PVAT), which… read more here.
Keywords: perivascular adipose; mesenteric artery; adipose tissue; melatonin ... See more keywords
Hesperidin reverses perivascular adipose-mediated aortic stiffness with aging
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2017.08.003
Abstract: ABSTRACT We tested the hypothesis that hesperidin would reverse age‐related aortic stiffness, perivascular adipose (PVAT) mediated‐arterial stiffening and PVAT advanced glycation end‐products (AGE) accumulation. Aortic pulse wave velocity (aPWV) and intrinsic mechanical stiffness, two measures… read more here.
Keywords: mechanical stiffness; stiffness; age; perivascular adipose ... See more keywords
Reply: New Aspects of Vasospastic Angina: Coronary Adventitial and Perivascular Adipose Tissue Inflammation.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.03.510
Abstract: We greatly appreciate Dr. Ciliberti and colleagues and Drs. Antonopoulos and Antoniades for their interests and comments on our recent study “Coronary adventitial and perivascular adipose tissue inflammation in patients with vasospastic angina” [(1)][1]. First,… read more here.
Keywords: coronary adventitial; perivascular adipose; adipose tissue; adventitial perivascular ... See more keywords
Inflammatory cells, ceramides, and expression of proteases in perivascular adipose tissue adjacent to human abdominal aortic aneurysms
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Vascular Surgery"
DOI: 10.1016/j.jvs.2015.12.056
Abstract: Background: Abdominal aortic aneurysm (AAA) is a deadly irreversible weakening and distension of the abdominal aortic wall. The pathogenesis of AAA remains poorly understood. Investigation into the physical and molecular characteristics of perivascular adipose tissue… read more here.
Keywords: perivascular adipose; tissue adjacent; adipose tissue; abdominal aortic ... See more keywords
Browning of Abdominal Aorta Perivascular Adipose Tissue Inhibits Adipose Tissue Inflammation.
Sign Up to like & getrecommendations! Published in 2017 at "Metabolic Syndrome and Related Disorders"
DOI: 10.1089/met.2017.0074
Abstract: Abstract Background: Perivascular adipose tissue (PVAT) can regulate vascular homeostasis by secreting various adipokines. This study investigated the effects of PVAT browning on its endocrine function. Methods: In the first section of our study, male… read more here.
Keywords: cold exposure; browning abdominal; perivascular adipose; tissue ... See more keywords
Role of Perivascular Adipose Tissue in Aorta Reactivity from Obese and Hyperglycemic CD-1 Mice: New Insights into Perivascular Adipose Tissue.
Sign Up to like & getrecommendations! Published in 2022 at "Metabolic syndrome and related disorders"
DOI: 10.1089/met.2022.0050
Abstract: Background: Perivascular adipose tissue (PVAT) plays an essential role in cardiovascular homeostasis. However, during obesity and diabetes, its role in vascular tone regulation is unclear. This study aimed to evaluate the function of the PVAT… read more here.
Keywords: perivascular adipose; adipose tissue; aorta reactivity; mice ... See more keywords
The role of perivascular adipose tissue in obesity‐induced vascular dysfunction
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DOI: 10.1111/bph.13650
Abstract: Under physiological conditions, perivascular adipose tissue (PVAT) attenuates agonist‐induced vasoconstriction by releasing vasoactive molecules including hydrogen peroxide, angiotensin 1–7, adiponectin, methyl palmitate, hydrogen sulfide, NO and leptin. This anticontractile effect of PVAT is lost under… read more here.
Keywords: dysfunction; perivascular adipose; obesity induced; adipose tissue ... See more keywords
New actions of an old friend: perivascular adipose tissue's adrenergic mechanisms
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DOI: 10.1111/bph.13663
Abstract: The revolutionary discovery in 1991 by Soltis and Cassis that perivascular adipose tissue (PVAT) has an anti‐contractile effect changed how we think about the vasculature. Most experiments on vascular pharmacology begin by removing the fat… read more here.
Keywords: system; perivascular adipose; pharmacology; adipose tissue ... See more keywords
Increased mitochondrial ROS generation mediates the loss of the anti‐contractile effects of perivascular adipose tissue in high‐fat diet obese mice
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DOI: 10.1111/bph.13687
Abstract: Obesity is associated with structural and functional changes in perivascular adipose tissue (PVAT), favouring release of reactive oxygen species (ROS), vasoconstrictor and proinflammatory factors. The cytokine TNF‐α induces vascular dysfunction and is produced by PVAT.… read more here.
Keywords: mitochondrial ros; perivascular adipose; tissue; generation ... See more keywords
Restoration of perivascular adipose tissue function in diet‐induced obese mice without changing bodyweight
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DOI: 10.1111/bph.13703
Abstract: We have recently shown that a reduced function of endothelial nitric oxide synthase (eNOS) in the perivascular adipose tissue (PVAT) contributes crucially to obesity‐induced vascular dysfunction in mice. The current study was conducted to test… read more here.
Keywords: tissue function; perivascular adipose; restoration perivascular; adipose tissue ... See more keywords
Adiponectin improves endothelial function in mesenteric arteries of rats fed a high‐fat diet: role of perivascular adipose tissue
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DOI: 10.1111/bph.13756
Abstract: Adiponectin, the most abundant peptide secreted by adipocytes, is involved in the regulation of energy metabolism and vascular physiology. Here, we have investigated the effects of exogenous administration of adiponectin on metabolism, vascular reactivity and… read more here.
Keywords: perivascular adipose; mesenteric arteries; fed high; high fat ... See more keywords