HIV-1 Tat disrupts blood-brain barrier integrity and increases phagocytic perivascular macrophages and microglia in the dorsal striatum of transgenic mice
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2016.12.073
Abstract: HIV-1 infection results in blood-brain barrier (BBB) disruption, which acts as a rate-limiting step for HIV-1 entry into the CNS and for subsequent neuroinflammatory/neurotoxic actions. One mechanism by which HIV may destabilize the BBB involves… read more here.
Keywords: phagocytic perivascular; macrophages microglia; hiv tat; perivascular macrophages ... See more keywords
Abstract 4119280: The role of colony-stimulating factor 1 receptor and perivascular macrophages in pulmonary arterial hypertension
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DOI: 10.1161/circ.150.suppl_1.4119280
Abstract: Background: Pulmonary arterial hypertension (PAH) is a life-threatening disease caused by pulmonary artery remodeling, inflammation, and altered immune responses. The proliferation of pulmonary arterial smooth muscle cells and the accumulation of perivascular macrophages are crucial… read more here.
Keywords: csf1r; arterial hypertension; perivascular macrophages; proliferation pulmonary ... See more keywords
Abstract 149: CD36 in Perivascular Macrophages Contributes to Neurovascular and Cognitive Dysfunction and Amyloid Angiopathy in Mice Overexpressing the Alzheimer Aβ Peptide
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DOI: 10.1161/str.49.suppl_1.149
Abstract: Amyloid-β (Aβ) exerts deleterious effects on the cerebral microcirculation, which may play a role in Alzheimer’s disease and mixed dementias. In mouse models of amyloid precursor protein (APP) over... read more here.
Keywords: abstract 149; contributes neurovascular; cd36 perivascular; perivascular macrophages ... See more keywords