Investigating the Interactions of Glioma Stem Cells in the Perivascular Niche at Single‐Cell Resolution using a Microfluidic Tumor Microenvironment Model
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DOI: 10.1002/advs.202201436
Abstract: The perivascular niche (PVN) is a glioblastoma tumor microenvironment (TME) that serves as a safe haven for glioma stem cells (GSCs), and acts as a reservoir that inevitably leads to tumor recurrence. Understanding cellular interactions… read more here.
Keywords: cell; glioma stem; tumor microenvironment; perivascular niche ... See more keywords
Perivascular Stromal Cells Instruct Glioblastoma Invasion, Proliferation, and Therapeutic Response within an Engineered Brain Perivascular Niche Model
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DOI: 10.1002/advs.202201888
Abstract: Glioblastoma (GBM) tumor cells are found in the perivascular niche microenvironment and are believed to associate closely with the brain microvasculature. However, it is largely unknown how the resident cells of the perivascular niche, such… read more here.
Keywords: brain perivascular; niche; perivascular niche; model ... See more keywords