Articles with "perk txnip" as a keyword



Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling

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Published in 2023 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2023.1170243

Abstract: Objective: Synovitis and fibrosis are common pathological features of knee osteoarthritis (KOA). The interaction of synovitis and fibrosis can promote KOA progression. Chrysin (CHR), a natural flavonoid, may treat inflammation and prevent fibrosis. However, the… read more here.

Keywords: nlrp3 signaling; synovitis fibrosis; perk txnip; fibrosis ... See more keywords