Increased Risk of Aortic Dissection with Perlecan Deficiency
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DOI: 10.3390/ijms23010315
Abstract: Perlecan (HSPG2), a basement membrane-type heparan sulfate proteoglycan, has been implicated in the development of aortic tissue. However, its role in the development and maintenance of the aortic wall remains unknown. Perlecan-deficient mice (Hspg2−/−-Tg: Perl… read more here.
Keywords: aortic tissue; risk; aortic dissection; perlecan deficiency ... See more keywords