Assessment of the Blood-Brain Barrier Permeability of Potential Neuroprotective Aurones in Parallel Artificial Membrane Permeability Assay and Porcine Brain Endothelial Cell Models.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2016.10.006
Abstract: Previously, several aurone derivatives were identified with promising neuroprotective activities. In developing these compounds to target the central nervous system (CNS), an assessment of their blood-brain barrier (BBB) permeability was performed using in vitro BBB models:… read more here.
Keywords: membrane permeability; artificial membrane; permeability; permeability assay ... See more keywords
Development of an On-Chip Antibiotic Permeability Assay With Single Molecule Detection Capability
Sign Up to like & getrecommendations! Published in 2018 at "IEEE Transactions on NanoBioscience"
DOI: 10.1109/tnb.2018.2809592
Abstract: Electrophysiology is the method of choice to characterize membrane channels. In this paper, we demonstrate a patch pipette based simple miniaturization that allows performing conductance measurements on a planar lipid bilayer in a microfluidic channel.… read more here.
Keywords: assay single; antibiotic permeability; permeability; chip antibiotic ... See more keywords