Bayesian Refinement of the Permeability-Limited Physiologically Based Pharmacokinetic Model for Perfluorooctanoic Acid in Male Rats.
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DOI: 10.1021/acs.chemrestox.1c00193
Abstract: Physiologically based pharmacokinetic (PBPK) modeling is a powerful technique to inform risk assessment of xenobiotic substances such as perfluorooctanoic acid (PFOA). In our previous study, a permeability-limited PBPK model was developed to simulate the toxicokinetics… read more here.
Keywords: based pharmacokinetic; permeability limited; physiologically based; permeability ... See more keywords