Histone H4 directly stimulates neutrophil activation through membrane permeabilization
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3a0620-342r
Abstract: Extracellular histones have been implicated as a cause of tissue inflammatory injury in a variety of disorders including sepsis, lung, and liver diseases. However, little is known about their interactions with neutrophils and how this… read more here.
Keywords: activation; neutrophil activation; permeabilization; histone directly ... See more keywords
Studying the Mechanism of Membrane Permeabilization Induced by Antimicrobial Peptides Using Patch-Clamp Techniques.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6737-7_18
Abstract: Many short peptides selectively permeabilize the bacteria plasma membrane, leading to their lyses and death: they are therefore a source of antibacterial molecules and inspiration for novel and more selective drugs, which may have wider… read more here.
Keywords: patch clamp; membrane; permeabilization; antimicrobial peptides ... See more keywords
Different permeabilization patterns of splenocytes and thymocytes to combination of pulsed electric and magnetic field treatments.
Sign Up to like & getrecommendations! Published in 2018 at "Bioelectrochemistry"
DOI: 10.1016/j.bioelechem.2018.04.006
Abstract: Genetic manipulation of T cells is frequently inefficient, however, when combined with physical methods (i.e. electroporation) a promising alliance with immunotherapy can be formed. This study presents new data on permeabilization of murine thymocytes and… read more here.
Keywords: combination; permeabilization patterns; pulsed electric; field ... See more keywords
Melittin-Induced Permeabilization, Re-sealing, and Re-permeabilization of E. coli Membranes.
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical journal"
DOI: 10.1016/j.bpj.2017.10.046
Abstract: The permeabilization of model lipid bilayers by cationic peptides has been studied extensively over decades, with the bee-sting toxin melittin perhaps serving as the canonical example. However, the relevance of these studies to the permeabilization… read more here.
Keywords: cell; induced permeabilization; gfp; melittin induced ... See more keywords
Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental cell"
DOI: 10.1016/j.devcel.2020.05.014
Abstract: Mitochondrial outer membrane permeabilization (MOMP) is a core event in apoptosis signaling. However, the underlying mechanism of BAX and BAK pore formation remains incompletely understood. We demonstrate that mitochondria are globally and dynamically targeted by… read more here.
Keywords: bax; apoptosis; momp; targeting mitochondria ... See more keywords
(-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance
Sign Up to like & getrecommendations! Published in 2018 at "Redox Biology"
DOI: 10.1016/j.redox.2017.11.002
Abstract: Increased permeability of the intestinal barrier is proposed as an underlying factor for obesity-associated pathologies. Consumption of high fat diets (HFD) is associated with increased intestinal permeabilization and increased paracellular transport of endotoxins which can… read more here.
Keywords: insulin; intestinal barrier; steatosis insulin; insulin resistance ... See more keywords
Imaging of photoacoustic-mediated permeabilization of giant unilamellar vesicles (GUVs)
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-82140-4
Abstract: Target delivery of large foreign materials to cells requires transient permeabilization of the cell membrane without toxicity. Giant unilamellar vesicles (GUVs) mimic the phospholipid bilayer of the cell membrane and are also useful drug delivery… read more here.
Keywords: vesicles guvs; permeabilization; giant unilamellar; unilamellar vesicles ... See more keywords
Adaptation of a bacterial membrane permeabilization assay for quantitative evaluation of benzalkonium chloride as a membrane-disrupting agent.
Sign Up to like & getrecommendations! Published in 2017 at "MedChemComm"
DOI: 10.1039/c7md00113d
Abstract: We describe the use of the ortho-nitrophenyl-β-galactoside (ONPG) assay developed by Lehrer et al. to which a new mathematical data treatment was applied. In this simplified assay, only one enzymatic assay is needed to provide… read more here.
Keywords: benzalkonium chloride; membrane permeabilization; membrane; permeabilization assay ... See more keywords
High-Pulsed Electromagnetic Field Generator for Contactless Permeabilization of Cells In Vitro
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Transactions on Magnetics"
DOI: 10.1109/tmag.2020.2979120
Abstract: High-intensity pulsed electromagnetic fields (HI-PEMFs) can be used for contactless permeabilization of biological cells and, thus, exploited for drug and gene delivery or other biomedical applications. Nevertheless, the availability of applicable technological setups is almost… read more here.
Keywords: permeabilization; pulsed electromagnetic; cells vitro; contactless permeabilization ... See more keywords
Influence of the fixation/permeabilization step on peptide nucleic acid fluorescence in situ hybridization (PNA-FISH) for the detection of bacteria
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0196522
Abstract: Fluorescence in situ Hybridization (FISH) is a versatile, widespread and widely- used technique in microbiology. The first step of FISH—fixation/permeabilization—is crucial to the outcome of the method. This work aimed to systematically evaluate fixation/permeabilization protocols… read more here.
Keywords: fixation permeabilization; fluorescence situ; situ hybridization; permeabilization ... See more keywords
Influence of Fixation and Permeabilization on the Mass Density of Single Cells: A Surface Plasmon Resonance Imaging Study
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2019.00588
Abstract: Fixation and permeabilization of cells and tissues are essential processes in biological techniques like immunofluorescence and immunohistochemistry for cell biology studies. In typical procedures, the biological samples are treated by paraformaldehyde and Triton X-100 to… read more here.
Keywords: fixation permeabilization; mass density; permeabilization; fixation ... See more keywords